Effect of acenocumarol and aspirin on platelet function, markers of thrombinemia, and intracardiac thrombosis in patients with atrial fibrillation

被引：0
|
作者：
Zharkova, T. V. [1 ]
Ataullakhanova, D. M. [1 ]
Bykova, E. S. [1 ]
Kropacheva, E. S. [1 ]
Dobrovolsky, A. B. [1 ]
Titaeva, E. V. [1 ]
Panchenko, E. P. [1 ]
机构：
[1] AL Myasnikov Cardiol Inst, Moscow 121552, Russia
来源：
KARDIOLOGIYA | 2007年 / 47卷 / 06期
关键词：
atrial fibrillation; thromboembolic complications; indirect anticoagulants; aspirin;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Patients with atrial fibrillation taking either indirect anticoagulant acenocumarol or most often prescribed antiaggregant aspirin were followed for 1 year. The results have shown that therapy with acenocumarol lowers content of D-dimer, prevents formation and promotes lysis of left auricular thrombi and lowers risk of development of ischemic stroke in patients with atrial fibrillation and high risk of thromboembolism. Therapy with aspirin in a dose providing maximal suppression of platelet function, does not lower D-dimer levels, does not promote lysis of left auricular thrombi and is inferior to acenocumarol in prevention of ischemic stroke.
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页码：31 / 36
页数：6
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