Synthesis of N-heteroarylamidines of 1,2,3-thiadiazole-4-carboxylic acid from 2-cyanothioacetamides and 5-azido-1-methyl-4-nitroimidazole

被引：8
|
作者：
Belyaev, Nikolay A. [1 ]
Beryozkina, Tetyana V. [1 ]
Bakulev, Vasiliy A. [1 ]
机构：
[1] Ural Fed Univ, 19 Mira St, Ekaterinburg 620002, Russia
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2016年 / 52卷 / 03期
基金：
俄罗斯科学基金会;
关键词：
azides; cyanothioacetamides; imidazoles; 1,2,3-thiadiazoles; thioamides; 1,2,3-triazoles; Cornforth rearrangement; REARRANGEMENTS; ATOM;
D O I：
10.1007/s10593-016-1861-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reaction of 2-cyanothioacetamides with 5-azido-1-methyl-4-nitroimidazole in ethanol in the presence of sodium ethoxide at 0A degrees D lead to the formation of previously unknown N-heteroarylamidines of 1,2,3-thiadiazole-4-carboxylic acid in 58-76% yields.
引用
收藏
页码：206 / 208
页数：3
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