Total, caffeinated and decaffeinated coffee and tea intake and gastric cancer risk: Results from the EPIC cohort study

被引：17

作者：

Sanikini, Harinakshi ^{[1
,2
,3
]}

Dik, Vincent K. ^{[1
]}

Siersema, Peter D. ^{[1
]}

Bhoo-Pathy, Nirmala ^{[4
,5
]}

Uiterwaal, Cuno S. P. M. ^{[6
]}

Peeters, Petra H. M. ^{[6
]}

Alez, Carlos A. Gonz ^{[7
]}

Zamora-Ros, Raul ^{[7
,8
]}

Overvad, Kim ^{[9
]}

Nneland, Anne Tj ^{[10
]}

Roswall, Nina ^{[10
]}

Boutron-Ruault, Marie-Christine ^{[3
,11
,12
]}

Fagherazzi, Guy ^{[3
,11
,12
]}

Racine, Antoine ^{[3
,11
,12
]}

Kuehn, Tilman ^{[13
]}

Katzke, Verena ^{[13
]}

Boeing, Heiner ^{[14
]}

Trichopoulou, Antonia ^{[15
,16
]}

Trichopoulos, Dimitrios ^{[15
,16
,17
]}

Lagiou, Pagona ^{[16
,17
,18
]}

Palli, Domenico ^{[19
]}

Grioni, Sara ^{[20
]}

Vineis, Paolo ^{[21
,22
]}

Tumino, Rosario ^{[23
,24
]}

Panico, Salvatore

Weiderpass, Elisabete

Skeie, Guri

Braaten, Tonje

Huerta, Jose Maria

Sanchez-Cantalejo, Emilio

Barricarte, Aurelio

Sonestedt, Emily

Wallstrom, Peter

Nilsson, Lena Maria

Johansson, Ingegerd

Bradbury, Kathryn E.

Khaw, Kay-Tee

Wareham, Nick

Huybrechts, Inge ^{[8
]}

Freisling, Heinz ^{[8
]}

Cross, Amanda J. ^{[22
]}

Riboli, Elio ^{[22
]}

Bueno-de-Mesquita, H. B ^{[1
,22
]}

机构：

[1] Univ Med Ctr Utrecht, Dept Gastroenterol & Hepatol, Utrecht, Netherlands

[2] INSERM, Ctr Res Epidemiol & Populat Hlth CESP, U1018, Environm Epidemiol Canc Team, Paris, France

[3] Univ Paris Sud, UMRS 1018, Paris, France

[4] Univ Malaya, Fac Med, Dept Social & Prevent Med, Kuala Lumpur, Malaysia

[5] Kuala Lumpur Hosp, Natl Clin Res Ctr, Kuala Lumpur, Malaysia

[6] Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands

[7] Catalan Inst Oncol ICO IDIBELL, Unit Nutr Environm & Canc, Barcelona, Spain

[8] Int Agcy Res Canc IARC WHO, Lyon, France

[9] Aarhus Univ, Epidemiol Sect, Dept Publ Hlth, Aarhus, Denmark

[10] Danish Canc Soc Res Ctr, Copenhagen, Denmark

[11] INSERM, Ctr Res Epidemiol & Populat Hlth CESP, Nutr Hormones & Womens Hlth Team, U1018, Paris, France

[12] IGR, Paris, France

[13] German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany

[14] Deutsch Inst Ernahrungsforsch, Dept Epidemiol, Potsdam, Nuthetal, Germany

[15] Hellen Hlth Fdn, Athens, Greece

[16] Acad Athens, Bur Epidemiol Res, Athens, Greece

[17] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA

[18] Univ Athens, Sch Med, Dept Hyg Epidemiol & Med Stat, GR-11527 Athens, Greece

[19] Canc Res & Prevent Inst ISPO, Mol & Nutr Epidemiol Unit, Florence, Italy

[20] Ist Nazl Tumori, Fdn IRCCS, Epidemiol & Prevent Unit, I-20133 Milan, Italy

[21] HuGeF Fdn, Turin, Italy

[22] Univ London Imperial Coll Sci Technol & Med, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England

[23] Civ MP Arezzo Hosp, Canc Registry, Asp Ragusa, Italy

[24] Civ MP Arezzo Hosp, Histopathol Unit, Asp Ragusa, Italy

来源：

INTERNATIONAL JOURNAL OF CANCER | 2015年 / 136卷 / 06期

基金：

英国医学研究理事会;

关键词：

coffee; caffeinated coffee; decaffeinated coffee; tea; gastric cancer; European Prospective Investigation into Cancer and Nutrition; STOMACH-CANCER; HELICOBACTER-PYLORI; UNITED-STATES; BLACK TEA; CONSUMPTION; ADENOCARCINOMA; ALCOHOL; METAANALYSIS; ESOPHAGUS; SMOKING;

D O I：

10.1002/ijc.29223

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Prospective studies examining the association between coffee and tea consumption and gastric cancer risk have shown inconsistent results. We investigated the association between coffee (total, caffeinated and decaffeinated) and tea consumption and the risk of gastric cancer by anatomical site and histological type in the European Prospective Investigation into Cancer and Nutrition study. Coffee and tea consumption were assessed by dietary questionnaires at baseline. Adjusted hazard ratios (HRs) were calculated using Cox regression models. During 11.6 years of follow up, 683 gastric adenocarcinoma cases were identified among 477,312 participants. We found no significant association between overall gastric cancer risk and consumption of total coffee (HR 1.09, 95%-confidence intervals [CI]: 0.84-1.43; quartile 4 vs. non/quartile 1), caffeinated coffee (HR 1.14, 95%-CI: 0.82-1.59; quartile 4 vs. non/quartile 1), decaffeinated coffee (HR 1.07, 95%-CI: 0.75-1.53; tertile 3 vs. non/tertile 1) and tea (HR 0.81, 95%-CI: 0.59-1.09; quartile 4 vs. non/quartile 1). When stratified by anatomical site, we observed a significant positive association between gastric cardia cancer risk and total coffee consumption per increment of 100 mL/day (HR 1.06, 95%-CI: 1.03-1.11). Similarly, a significant positive association was observed between gastric cardia cancer risk and caffeinated coffee consumption (HR 1.98, 95%-CI: 1.16-3.36, p-trend=0.06; quartile 3 vs. non/quartile 1) and per increment of 100 mL/day (HR 1.09, 95%-CI: 1.04-1.14). In conclusion, consumption of total, caffeinated and decaffeinated coffee and tea is not associated with overall gastric cancer risk. However, total and caffeinated coffee consumption may be associated with an increased risk of gastric cardia cancer. Further prospective studies are needed to rule out chance or confounding. What's New? Can drinking coffee or tea lead to cancer? Can they protect against cancer? These popular drinks certainly contain antioxidants, but despite many investigations into the question, we still have no clear answer. A new study has plied the data from the European Prospective Investigation into Cancer and Nutrition (EPIC) in search of a link. Participants self-reported their coffee and tea consumption by questionnaire. The authors found no link between drinking tea or coffee - with or without caffeine - and overall risk of gastric cancer; they did discern a slight increase in gastric cardia cancer with consumption of caffeinated coffee.

引用

页码：E720 / E730

页数：11

共 50 条

[1] Caffeinated and decaffeinated coffee intake and colorectal cancer: A risk assessment
Kawada, Tomoyuki
[J]. CANCER EPIDEMIOLOGY, 2020, 69
[2] Caffeinated and decaffeinated coffee and tea intakes and risk of colorectal cancer in a large prospective study
Sinha, Rashmi
Cross, Amanda J.
Daniel, Carrie R.
Graubard, Barry I.
Wu, Jennifer W.
Hollenbeck, Albert R.
Gunter, Marc J.
Park, Yikyung
Freedman, Neal D.
[J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 2012, 96 (02): : 374 - 381
[3] Coffee, Decaffeinated Coffee, Tea Intake, and Risk of Renal Cell Cancer
Montella, Maurizio
Tramacere, Irene
Tavani, Alessandra
Gallus, Silvano
Crispo, Anna
Talamini, Renato
Dal Maso, Luigino
Ramazzotti, Valerio
Galeone, Carlotta
Franceschi, Silvia
La Vecchia, Carlo
[J]. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2009, 61 (01): : 76 - 80
[4] Intake of Coffee, Decaffeinated Coffee, or Tea Does Not Affect Risk for Pancreatic Cancer: Results From the European Prospective Investigation into Nutrition and Cancer Study
Bhoo-Pathy, Nirmala
Uiterwaal, Cuno S. P. M.
Dik, Vincent K.
Jeurnink, Suzanne M.
Bech, Bodil H.
Overvad, Kim
Halkjaer, Jytte
Tjonneland, Anne
Boutron-Ruault, Marie-Christine
Fagherazzi, Guy
Racine, Antoine
Katzke, Verena A.
Li, Kuanrong
Boeing, Heiner
Floegel, Anna
Androulidaki, Anna
Bamia, Christina
Trichopoulou, Antonia
Masala, Giovanna
Panico, Salvatore
Crosignani, Paolo
Tumino, Rosario
Vineis, Paolo
Peeters, Petra H. M.
Gavrilyuk, Oxana
Skeie, Guri
Weiderpass, Elisabete
Duell, Eric J.
Arguelles, Marcial
Molina-Montes, Esther
Navarro, Carmen
Ardanaz, Eva
Dorronsoro, Miren
Lindkvist, Bjorn
Wallstrom, Peter
Sund, Malin
Ye, Weimin
Khaw, Kay-Tee
Wareham, Nick
Key, Timothy J.
Travis, Ruth C.
Duarte-Salles, Talita
Freisling, Heinz
Licaj, Idlir
Gallo, Valentina
Michaud, Dominique S.
Riboli, Elio
Bueno-De-Mesquita, H. Bas
[J]. CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2013, 11 (11) : 1486 - 1492
[5] Caffeinated Coffee, Decaffeinated Coffee and Endometrial Cancer Risk: A Prospective Cohort Study among US Postmenopausal Women
Giri, Ayush
Sturgeon, Susan R.
Luisi, Nicole
Bertone-Johnson, Elizabeth
Balasubramanian, Raji
Reeves, Katherine W.
[J]. NUTRIENTS, 2011, 3 (11) : 937 - 950
[6] Response to letter to the editor: Caffeinated and decaffeinated coffee intake and colorectal cancer: A risk assessment
Um, Caroline Y.
McCullough, Marjorie L.
Gapstur, Susan M.
[J]. CANCER EPIDEMIOLOGY, 2020, 69
[7] Coffee and tea intake and risk of brain tumors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study
Michaud, Dominique S.
Gallo, Valentina
Schlehofer, Brigitte
Tjonneland, Anne
Olsen, Anja
Overvad, Kim
Dahm, Christina C.
Teucher, Birgit
Lukanova, Annekatrin
Boeing, Heiner
Schutze, Madlen
Trichopoulou, Antonia
Lagiou, Pagona
Kyrozis, Andreas
Sacerdote, Carlotta
Krogh, Vittorio
Masala, Giovanna
Tumino, Rosario
Mattiello, Amalia
de Mesquita, H. Bas Bueno
Ros, Martine M.
Peeters, Petra H. M.
van Gils, Carla H.
Skeie, Guri
Engeset, Dagrun
Parr, Christine L.
Ardanaz, Eva
Chirlaque, Maria-Dolores
Dorronsoto, Miren
Jose Sanchez, Maria
Arguelles, Marcial
Jakszyn, Paula
Nilsson, Lena M.
Melin, Beatrice S.
Manjer, Jonas
Wirfalt, Elisabet
Khaw, Kay-Tee
Wareham, Nick
Allen, Naomi E.
Key, Timothy J.
Romieu, Isabelle
Vinets, Paolo
Riboli, Elio
[J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 2010, 92 (05): : 1145 - 1150
[8] Intake of coffee and tea and risk of ovarian cancer: A prospective cohort study
Silvera, Stephanie A. N.
Jain, Meera
Howe, Geoffrey R.
Miller, Anthony B.
Rohan, Thomas E.
[J]. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2007, 58 (01): : 22 - 27
[9] Are coffee, tea, and total fluid consumption associated with bladder cancer risk? Results from the Netherlands Cohort Study
Zeegers, MPA
Dorant, E
Goldbohm, RA
van den Brandt, PA
[J]. CANCER CAUSES & CONTROL, 2001, 12 (03) : 231 - 238
[10] CAFFEINATED OR DECAFFEINATED COFFEE CONSUMPTION AND RISK OF CANCER INCIDENCE: A META-ANALYSIS OF PROSPECTIVE COHORT STUDIES
Nguyen, T. N.
Eng, D.
Kawasumi, M.
[J]. JOURNAL OF INVESTIGATIVE MEDICINE, 2021, 69 (01) : 164 - 164

← 1 2 3 4 5 →