Making the invisible enemy visible

被引：19

作者：

Croll, Tristan I. ^{[1
]}

Diederichs, Kay ^{[2
]}

Fischer, Florens ^{[3
,5
]}

Fyfe, Cameron D. ^{[4
]}

Gao, Yunyun ^{[3
,5
]}

Horrell, Sam ^{[6
]}

Joseph, Agnel Praveen ^{[7
]}

Kandler, Luise ^{[3
,5
]}

Kippes, Oliver ^{[3
,5
]}

Kirsten, Ferdinand ^{[3
,5
]}

Mueller, Konstantin ^{[5
]}

Nolte, Kristopher ^{[3
,5
]}

Payne, Alexander M. ^{[8
]}

Reeves, Matthew ^{[5
]}

Richardson, Jane S. ^{[9
]}

Santoni, Gianluca ^{[10
]}

Staeb, Sabrina ^{[3
,5
]}

Tronrud, Dale E. ^{[11
]}

von Soosten, Lea C. ^{[3
,5
]}

Williams, Christopher J. ^{[9
]}

Thorn, Andrea ^{[3
,5
]}

机构：

[1] Univ Cambridge, CIMR, Cambridge, England

[2] Univ Konstanz, Constance, Germany

[3] Univ Hamburg, Inst Nanostruktur & Festkorperphys, Hamburg, Germany

[4] INRAE, Micalis Inst, Jouy En Josas, France

[5] Julius Maximilians Univ Wurzburg, Rudolf Virchow Zentrum, Wurzburg, Germany

[6] Diamond Light Source, Didcot, Oxon, England

[7] Sci & Technol Facil Council, Swindon, Wilts, England

[8] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA

[9] Duke Univ, Durham, NC USA

[10] European Synchrotron Radiat Facil, Grenoble, France

[11] Oregon State Univ, Corvallis, OR 97331 USA

来源：

NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2021年 / 28卷 / 05期

基金：

英国惠康基金; 美国国家卫生研究院;

关键词：

DATA RESOURCE; SOFTWARE; EM;

D O I：

10.1038/s41594-021-00593-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Structural biology plays a crucial role in the fight against COVID-19, permitting us to 'see' and understand SARS-CoV-2. However, the macromolecular structures of SARS-CoV-2 proteins that were solved with great speed and urgency can contain errors that may hinder drug design. The Coronavirus Structural Task Force has been working behind the scenes to evaluate and improve these structures, making the results freely available at https://insidecorona.net/.

引用

页码：404 / 408

页数：5

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[1] Making the invisible enemy visible
Tristan I. Croll
Kay Diederichs
Florens Fischer
Cameron D. Fyfe
Yunyun Gao
Sam Horrell
Agnel Praveen Joseph
Luise Kandler
Oliver Kippes
Ferdinand Kirsten
Konstantin Müller
Kristopher Nolte
Alexander M. Payne
Matthew Reeves
Jane S. Richardson
Gianluca Santoni
Sabrina Stäb
Dale E. Tronrud
Lea C. von Soosten
Christopher J. Williams
Andrea Thorn
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