Forty anxious day case patients undergoing extraction of third molar teeth under local anaesthesia with sedation, were studied in a randomised double-blind controlled trial. A target-controlled infusion of propofol was compared with patient-controlled propofol for sedation, combined with a small dose of midazolam to improve amnesia. The objectives of the study were to measure the total dose of propofol used by the two groups and assess recovery and patient satisfaction. The mean dose of propofol used in the patient-controlled sedation group was significantly less than the target-controlled group (p < 0.00007). Five patients became over-sedated in the target-controlled group compared with none in the patient-controlled group. Only one of the three tests of performance showed that the target-controlled patients were more sedated. Patient satisfaction was high in both groups despite a greater recollection of events in the patient-controlled group.
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Univ Helsinki, Cent Hosp, Dept Anesthesia & Intens Care Med, Helsinki 00029, FinlandUniv Helsinki, Cent Hosp, Dept Anesthesia & Intens Care Med, Helsinki 00029, Finland
Mazanikov, Max
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Udd, Marianne
Kylanpaa, Leena
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Univ Helsinki, Cent Hosp, Dept Gastrointestinal & Gen Surg, Helsinki 00029, FinlandUniv Helsinki, Cent Hosp, Dept Anesthesia & Intens Care Med, Helsinki 00029, Finland
Kylanpaa, Leena
Mustonen, Harri
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Univ Helsinki, Cent Hosp, Dept Gastrointestinal & Gen Surg, Helsinki 00029, FinlandUniv Helsinki, Cent Hosp, Dept Anesthesia & Intens Care Med, Helsinki 00029, Finland
Mustonen, Harri
Lindstrom, Outi
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Univ Helsinki, Cent Hosp, Dept Gastrointestinal & Gen Surg, Helsinki 00029, FinlandUniv Helsinki, Cent Hosp, Dept Anesthesia & Intens Care Med, Helsinki 00029, Finland
Lindstrom, Outi
Farkkila, Martti
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机构:Univ Helsinki, Cent Hosp, Dept Anesthesia & Intens Care Med, Helsinki 00029, Finland
Farkkila, Martti
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Halttunen, Jorma
Poyhia, Reino
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Univ Helsinki, Cent Hosp, Dept Anesthesia & Intens Care Med, Helsinki 00029, FinlandUniv Helsinki, Cent Hosp, Dept Anesthesia & Intens Care Med, Helsinki 00029, Finland
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Univ Hull, Acad Surg Unit, Kingston Upon Hull HU6 7RX, N Humberside, England
Castle Hill Hosp, Kingston Upon Hull, N Humberside, EnglandUniv Hull, Acad Surg Unit, Kingston Upon Hull HU6 7RX, N Humberside, England
Balaji, P.
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Gardiner, A.
Culbert, B.
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Univ Hull, Acad Surg Unit, Kingston Upon Hull HU6 7RX, N Humberside, England
Castle Hill Hosp, Kingston Upon Hull, N Humberside, EnglandUniv Hull, Acad Surg Unit, Kingston Upon Hull HU6 7RX, N Humberside, England
Culbert, B.
Monson, J. R. T.
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Univ Rochester, Med Ctr, Div Colorectal Surg, Rochester, NY 14642 USAUniv Hull, Acad Surg Unit, Kingston Upon Hull HU6 7RX, N Humberside, England
Monson, J. R. T.
Duthie, G. S.
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Univ Hull, Acad Surg Unit, Kingston Upon Hull HU6 7RX, N Humberside, England
Castle Hill Hosp, Kingston Upon Hull, N Humberside, EnglandUniv Hull, Acad Surg Unit, Kingston Upon Hull HU6 7RX, N Humberside, England