Deep Screening of Guide RNAs Enables Therapeutic RNA Editing with Endogenous ADAR

被引：0
|
作者：
Booth, Brian J. [1 ]
Savva, Yiannis [1 ]
Byrne, Susan [1 ]
Sullivan, Rick [1 ]
Burleigh, Stephen [1 ]
Briggs, Adrian W. [1 ]
机构：
[1] Shape Therapeut, Seattle, WA USA
来源：
MOLECULAR THERAPY | 2021年 / 29卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
379
引用
收藏
页码：187 / 187
页数：1
相关论文
共 50 条
  • [1] CLUSTER guide RNAs enable precise and efficient RNA editing with endogenous ADAR enzymes in vivo
    Philipp Reautschnig
    Nicolai Wahn
    Jacqueline Wettengel
    Annika E. Schulz
    Ngadhnjim Latifi
    Paul Vogel
    Tae-Won Kang
    Laura S. Pfeiffer
    Christine Zarges
    Ulrike Naumann
    Lars Zender
    Jin Billy Li
    Thorsten Stafforst
    Nature Biotechnology, 2022, 40 : 759 - 768
  • [2] CLUSTER guide RNAs enable precise and efficient RNA editing with endogenous ADAR enzymes in vivo
    Reautschnig, Philipp
    Wahn, Nicolai
    Wettengel, Jacqueline
    Schulz, Annika E.
    Latifi, Ngadhnjim
    Vogel, Paul
    Kang, Tae-Won
    Pfeiffer, Laura S.
    Zarges, Christine
    Naumann, Ulrike
    Zender, Lars
    Li, Jin Billy
    Stafforst, Thorsten
    NATURE BIOTECHNOLOGY, 2022, 40 (05) : 759 - +
  • [3] Improved RNA base editing with guide RNAs mimicking highly edited endogenous ADAR substrates
    Sun, Yuanfan
    Cao, Yong
    Song, Yulong
    Li, Jin
    Hou, Yongheng
    Huang, Wen
    Xie, Guodong
    Yang, Wenbing
    Zhang, Rui
    NATURE BIOTECHNOLOGY, 2025,
  • [4] RNA editing with endogenous ADAR
    Rusk, Nicole
    NATURE METHODS, 2019, 16 (04) : 285 - 285
  • [5] Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs
    Qu, Liang
    Yi, Zongyi
    Zhu, Shiyou
    Wang, Chunhui
    Cao, Zhongzheng
    Zhou, Zhuo
    Yuan, Pengfei
    Yu, Ying
    Tian, Feng
    Liu, Zhiheng
    Bao, Ying
    Zhao, Yanxia
    Wei, Wensheng
    NATURE BIOTECHNOLOGY, 2019, 37 (09) : 1059 - +
  • [6] Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs
    Liang Qu
    Zongyi Yi
    Shiyou Zhu
    Chunhui Wang
    Zhongzheng Cao
    Zhuo Zhou
    Pengfei Yuan
    Ying Yu
    Feng Tian
    Zhiheng Liu
    Ying Bao
    Yanxia Zhao
    Wensheng Wei
    Nature Biotechnology, 2019, 37 : 1059 - 1069
  • [7] Author Correction: Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs
    Liang Qu
    Zongyi Yi
    Shiyou Zhu
    Chunhui Wang
    Zhongzheng Cao
    Zhuo Zhou
    Pengfei Yuan
    Ying Yu
    Feng Tian
    Zhiheng Liu
    Ying Bao
    Yanxia Zhao
    Wensheng Wei
    Nature Biotechnology, 2019, 37 : 1380 - 1380
  • [8] Enhancing RNA editing efficiency and specificity with engineered ADAR2 guide RNAs
    Ai, Xilei
    Ding, Sheng
    Zhou, Shan
    Du, Feng
    Liu, Shuai
    Cui, Xin
    Dong, Juan
    Huang, Xin
    Tang, Zhuo
    MOLECULAR THERAPY NUCLEIC ACIDS, 2025, 36 (01):
  • [9] Programmable RNA editing by recruiting endogenous ADAR using engineered RNAs (vol 37, pg 1059, 2019)
    Qu, Liang
    Yi, Zongyi
    Zhu, Shiyou
    Wang, Chunhui
    Cao, Zhongzheng
    Zhou, Zhuo
    Yuan, Pengfei
    Yu, Ying
    Tian, Feng
    Liu, Zhiheng
    Bao, Ying
    Zhao, Yanxia
    Wei, Wensheng
    NATURE BIOTECHNOLOGY, 2019, 37 (11) : 1380 - 1380
  • [10] Light-triggered site-directed RNA editing by endogenous ADAR1 with photolabile guide RNA
    Zhang, Yu
    Feng, Di
    Mu, Guanqun
    Wang, Qian
    Wang, Jing
    Luo, Yun
    Tang, Xinjing
    CELL CHEMICAL BIOLOGY, 2023, 30 (06) : 672 - +
12345