Cancer Physical Hallmarks as New Targets for Improved Immunotherapy

被引：21
|
作者：
Guo, Hui [1 ,2 ]
Zhang, Tian [1 ,2 ]
Yu, Yang [1 ,2 ]
Xu, Feng [2 ,3 ]
机构：
[1] Xi An Jiao Tong Univ, Dept Med Oncol, Affiliated Hosp 1, Xian 710061, Peoples R China
[2] Xi An Jiao Tong Univ, BEBC, Xian 710049, Peoples R China
[3] Xi An Jiao Tong Univ, Sch Life Sci & Technol, MOE Key Lab Biomed Informat Engn, Xian 710049, Peoples R China
来源：
TRENDS IN CELL BIOLOGY | 2021年 / 31卷 / 07期
基金：
中国博士后科学基金; 中国国家自然科学基金;
关键词：
D O I：
10.1016/j.tcb.2021.03.011
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
A low response rate is the major challenge for existing cancer immunotherapies. Physical cues in the tumor microenvironment (TME) have been recognized as new hallmarks of cancer, which may synergistically contribute to low immunotherapy response. Recent evidence indicates that the physical hallmarks of cancer hold great potential as new targets for improved immunotherapy.
引用
收藏
页码：520 / 524
页数：5
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