L-Proline triflate as an efficient and reusable catalyst for the one-pot synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles

被引：13

作者：

Li, Jianjun ^{[1
]}

Lin, Shouwang ^{[1
]}

Dai, Jiajia ^{[1
]}

Su, Weike ^{[1
]}

机构：

[1] Zhejiang Univ Technol, Coll Pharmaceut Sci, Minist Educ, Key Lab Pharmaceut Engn, Hangzhou 310014, Zhejiang, Peoples R China

来源：

JOURNAL OF CHEMICAL RESEARCH | 2010年 / 04期

基金：

中国国家自然科学基金;

关键词：

L-proline triflate; multicomponent reaction; 2,4,5-trisubstituted imidazoles; 1,2,4,5-tetrasubstituted imidazoles; TETRASUBSTITUTED IMIDAZOLES; MICROWAVE IRRADIATION; HIGHLY EFFICIENT; SILICA; ESTERIFICATION; ANALOGS; SYSTEM; KINASE;

D O I：

10.3184/030823410X12698803608765

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

L-Proline triflate has been used as an efficient catalyst for an improved and rapid one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles in good yields. The benefit of this approach is its operational simplicity and the catalyst can be easily recovered and reused without any loss of activity.

引用

页码：196 / 199

页数：4

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