Identification of intracellular gold nanoparticles using surface-enhanced Raman scattering

被引：15

作者：

Xie, Hai-nan ^{[1
,2
]}

Lin, Yiyang ^{[1
,2
]}

Mazo, Manuel ^{[1
,2
]}

Chiappini, Ciro ^{[1
,2
]}

Sanchez-Iglesias, Ana ^{[3
]}

Liz-Marzan, Luis M. ^{[3
,4
]}

Stevens, Molly M. ^{[1
,2
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Mat, Dept Bioengn, London SW7 2AZ, England

[2] Univ London Imperial Coll Sci Technol & Med, Inst Biomed Engn, London SW7 2AZ, England

[3] CIC BiomaGUNE, BioNanoPlasmon Lab, Donostia San Sebastian 20009, Spain

[4] Basque Fdn Sci, Ikerbasque, Bilbao 48011, Spain

来源：

NANOSCALE | 2014年 / 6卷 / 21期

关键词：

MEMBRANE-PERMEABILITY; PLASMON RESONANCE; CONTRAST AGENTS; COLLOIDAL GOLD; MICROSCOPY; DELIVERY; SPECTROSCOPY; SERS; CELL;

D O I：

10.1039/c4nr04687k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The identification of intracellular distributions of noble metal nanoparticles is of great utility for many biomedical applications. We present an effective method to distinguish intracellular from extracellular nanoparticles by selectively quenching the SERS signals from dye molecules adsorbed onto star-shaped gold nanoparticles that have not been internalized by cells.

引用

页码：12403 / 12407

页数：5

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