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- [1] Naloxegol Accelerates Time to First Spontaneous Bowel Movement (SBM) and Complete SBM (CSBM) With Predictable Efficacy in Patients With Extreme Opioid-Induced Constipation (OIC): A Pooled Analysis of Two Phase 3 Trials [J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2021, 116 : S221 - S221