Delivery of endostatin in experimental cancer therapy

被引：0
|
作者：
Sorensen, DR [1 ]
Read, TA
机构：
[1] Univ Oslo, Rikshosp, Dept Comparat Med, N-0027 Oslo, Norway
[2] Univ Bergen, Dept Anat & Cell Biol, N-5020 Bergen, Norway
来源：
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY | 2002年 / 83卷 / 06期
关键词：
cancer; delivery; endostatin;
D O I：
暂无
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Endostatin, the 20 kDa C-terminal fragment of collagen XVIII, has been shown to be an effective inhibitor of tumour angiogenesis and growth in different experimental systems and is currently in Phase II/III clinical trials. One challenging aspect of anti-angiogenic treatment is the mode of delivery of the active compound. In this paper we review some of the basic knowledge of endostatin and look specifically into the different possible ways in which endostatin may be administered.
引用
收藏
页码：265 / 274
页数：10
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