Sex-determining genes

被引：10
|
作者：
McElreavey, K [1 ]
Fellous, M [1 ]
机构：
[1] Inst Pasteur, Immunogenet Humaine, F-75724 Paris 15, France
来源：
TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1997年 / 8卷 / 09期
关键词：
D O I：
10.1016/S1043-2760(97)00135-5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Recently, a number of genes have been identified that are associated with a failure of human sex determination, including WT1, DAX-1, SOX9, ATRX, and the Y-linked testis determination gene, SRY. Most cases of human sex reversal, XY females and XX males, do not, however, appear to be caused by mutations in these genes. This review highlights recent advances in this field and discusses the prospects of identifying genes in the sex-determining pathway. (C) 1997, Elsevier Science Inc.
引用
收藏
页码：342 / 346
页数：5
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