Ligand-Selective Wnt Receptor Complexes in CNS Blood Vessels: RECK and GPR124 Plugged In

被引：9
|
作者：
Junge, Harald J. [1 ]
机构：
[1] Univ Colorado, Dept Mol Cellular & Dev Biol, Boulder, CO 80309 USA
来源：
NEURON | 2017年 / 95卷 / 05期
关键词：
BRAIN-BARRIER INTEGRITY;
D O I：
10.1016/j.neuron.2017.08.026
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
CNS angiogenesis and blood-brain barrier integrity are controlled by the canonical Wnt pathway. In this issue of Neuron, Cho et al. (2017) use advanced mouse genetics and biochemical experiments to unravel the ligand-specific association of membrane proteins GPR124 and RECK with Wnt receptor complexes.
引用
收藏
页码：983 / 985
页数：3
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