Anti-inflammatory and antinociceptive activities of Loasa speciosa in rats and mice

被引:15
|
作者
Badilla, B [1 ]
Arias, AY
Arias, M
Mora, GA
Poveda, LJ
机构
[1] Univ Costa Rica, Fac Farm, INIFAR, San Jose 2060, Costa Rica
[2] Univ Costa Rica, CIPRONA, San Jose 2060, Costa Rica
[3] Univ Nacl, Fac Ciencias Ambientales, Herbario Juvenal Valerio Rojas, Heredia, Costa Rica
关键词
Loasa speciosa; aqueous extract; anti-inflammatory; antinociceptive; rat paw edema;
D O I
10.1016/S0367-326X(02)00299-X
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
In the range of doses of 250-500 mg/kg (given i.p.) the aqueous extract of Loasa speciosa leaves showed an inhibitory effect on leukocyte migration, and a reduction on the pleural exudate, as well as dose-dependent anti-inflammatory and peripheral antinociceptive activities. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:45 / 51
页数:7
相关论文
共 50 条
  • [1] Anti-inflammatory and Antinociceptive Activities of Azadirachtin in Mice
    Soares, Darly G.
    Godin, Adriana M.
    Menezes, Raquel R.
    Nogueira, Rafaela D.
    Brito, Ana Mercy S.
    Melo, Ivo S. F.
    Coura, Giovanna Maria E.
    Souza, Danielle G.
    Amaral, Flavio A.
    Paulino, Tony P.
    Coelho, Marcio M.
    Machado, Renes R.
    [J]. PLANTA MEDICA, 2014, 80 (8-9) : 630 - 636
  • [2] Antinociceptive and anti-inflammatory activities of crude extracts of Ipomoea involucrata leaves in mice and rats
    Uche Fidelia Ijeoma
    Shorinwa Olusayo Aderonke
    Okorie Ogbonna
    Mgbahurike Amaka Augustina
    Chijioke-Nwauche Ifeyinwa
    [J]. Asian Pacific Journal of Tropical Medicine, 2011, 4 (02) : 121 - 124
  • [3] Antinociceptive and anti-inflammatory activities of crude extracts of Ipomoea involucrata leaves in mice and rats
    Ijeoma, Uche Fidelia
    Aderonke, Shorinwa Olusayo
    Ogbonna, Okorie
    Augustina, Mgbahurike Amaka
    Ifeyinwa, Chijioke-Nwauche
    [J]. ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2011, 4 (02) : 121 - 124
  • [4] Antinociceptive and Anti-Inflammatory Activities of Cuscuta chinensis Seeds in Mice
    Liao, Jung-Chun
    Chang, Wen-Te
    Lee, Meng-Shiou
    Chiu, Yung-Jia
    Chao, Wei-Kai
    Lin, Ying-Chih
    Lin, Ming-Kuem
    Peng, Wen-Huang
    [J]. AMERICAN JOURNAL OF CHINESE MEDICINE, 2014, 42 (01): : 223 - 242
  • [5] Anti-inflammatory and antinociceptive properties of dantrolene sodium in rats and mice
    Büyükokuroglu, ME
    [J]. PHARMACOLOGICAL RESEARCH, 2002, 45 (06) : 455 - 460
  • [6] Antinociceptive and anti-inflammatory activities of butein in different nociceptive and inflammatory mice models
    Gao, Li
    Cui, Shasha
    Huang, Zhiqiang
    Cui, Hailong
    Alahmadi, Tahani Awad
    Manikandan, Velu
    [J]. SAUDI JOURNAL OF BIOLOGICAL SCIENCES, 2021, 28 (12) : 7090 - 7097
  • [7] Antinociceptive and anti-inflammatory activities of Tabernaemontana catharinensis
    Gomes, R. C.
    Neto, A. C.
    Melo, V. L.
    Fernandes, V. C.
    Dagrava, G.
    Santos, W. S.
    Pereira, P. S.
    Couto, L. B.
    Beleboni, R. O.
    [J]. PHARMACEUTICAL BIOLOGY, 2009, 47 (04) : 372 - 376
  • [8] Antinociceptive and anti-inflammatory activities of Viburnum lantana
    Yilmaz, B. Sever
    Citoglu, G. Saltan
    Altun, M. L.
    Ozbek, H.
    [J]. PHARMACEUTICAL BIOLOGY, 2007, 45 (03) : 241 - 245
  • [9] Antinociceptive and anti-inflammatory activities and acute toxicity of Achillea nobilis subsp neilreichii extract in mice and rats
    Karabay-Yavasoglu, N. U.
    Karamenderes, C.
    Baykan, S.
    Apaydin, S.
    [J]. PHARMACEUTICAL BIOLOGY, 2007, 45 (02) : 162 - 168
  • [10] Anti-inflammatory and antinociceptive activities of Campomanesia adamantium
    Ferreira, Leidiane C.
    Grabe-Guimaraes, Andrea
    de Paula, Carmen A.
    Michel, Marcela C. P.
    Guimaraes, Raquel G.
    Rezende, Simone A.
    de Souza Filho, Jose D.
    Saude-Guimaraes, Denia A.
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 2013, 145 (01) : 100 - 108