The Prevalence and Related Effects of HIV Drug-Resistant Strains Against Antiretroviral Therapy in China

被引：2
|
作者：
Xing, Hui [1 ]
Ruan, Yuhua [1 ]
Liao, Lingjie [1 ]
Shao, Yingming [1 ]
机构：
[1] Chinese Ctr Dis Control & Prevent, Collaborat Innovat Ctr Diag & Treatment Infect Di, State Key Lab Infect Dis Prevent & Control, Natl Ctr AIDS STD Control & Prevent, 155 Changbai Rd, Beijing 102206, Peoples R China
来源：
INFECTIOUS MICROBES & DISEASES | 2022年 / 4卷 / 02期
关键词：
antiretroviral treatment (ART); drug resistance; human immunodeficiency virus (HIV); RITONAVIR PLUS LAMIVUDINE; VIROLOGICAL FAILURE; INFECTED PATIENTS; TRIPLE TREATMENT; DUAL TREATMENT; OPEN-LABEL; FOLLOW-UP; MUTATIONS; MORTALITY; COHORT;
D O I：
10.1097/IM9.0000000000000091
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Anti-human immunodeficiency virus (HIV) treatment resistance surveillance has been going on for nearly 18 years in China. In this paper, we review the prevalence in China of resistance to reverse transcriptase and protease inhibitors in the HIV-infected population receiving antiretroviral therapy (ART) and the population that stopped ART in recent years. Drug resistance is an important factor affecting the death of patients with acquired immune deficiency syndrome (AIDS). With the extension of the duration of ART and the expansion of the population receiving ART, especially the widespread promotion of preventive drugs before and after exposure, it is important to obtain insight into the prevalence and types of drug-resistant strains and their impact on the overall AIDS prevention and treatment effect.
引用
收藏
页码：71 / 74
页数：4
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