Generalized lichen nitidus with involvement of the palms following interferon α treatment

被引：18
|
作者：
Scheler, Marina
Proelss, Julia
Braeuninger, Wolfgang
Bieber, Thomas
Wenzel, Joerg
机构：
[1] Univ Bonn, Dept Dermatol, DE-53105 Bonn, Germany
[2] Johannes Gutenberg Univ Mainz, Dept Dermatol, D-6500 Mainz, Germany
来源：
DERMATOLOGY | 2007年 / 215卷 / 03期
关键词：
lichen nitidus; interferon alpha; hepatitis C; lichen planus;
D O I：
10.1159/000106582
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Lichen nitidus is an uncommon dermatosis of unknown etiology. Here we present the case of a generalized lichen nitidus with involvement of the palms in a patient with hepatitis C after systemic treatment with interferon alpha and ribavirin. Furthermore in our patient we could show a strong lesional expression of MxA, a protein specifically induced by type I interferon. It is tempting to speculate that interferon alpha may be involved in the pathogenesis of lichen nitidus. Copyright (C) 2007 S. Karger AG, Basel.
引用
收藏
页码：236 / 239
页数：4
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