A general synthesis of novel conformationally restricted arginine side-chain mimetics

被引：1
|
作者：
Masic, LP [1 ]
Kikelj, D [1 ]
机构：
[1] Univ Ljubljana, Fac Pharm, Ljubljana 1000, Slovenia
来源：
TETRAHEDRON LETTERS | 2000年 / 41卷 / 29期
关键词：
arginine side-chain mimetics; serine proteases;
D O I：
10.1016/S0040-4039(00)00869-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
6-(Aminomethyl)-5,6,7,8-tetrahydro-2-quinazolinamine and 4,5,6,7-tetrahydro-2H-indazol-5-ylmethanamine were synthesized as novel conformationally restricted arginine side-chain mimetics, designed for incorporation into trypsin-like serine protease inhibitors. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：5589 / 5592
页数：4
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