Long-term implantable glucose biosensors

被引：47

作者：

Bobrowski, Tim ^{[1
]}

Schuhmann, Wolfgang ^{[1
]}

机构：

[1] Ruhr Univ Bochum, CES, Analyt Chem, Univ Str 150, D-44780 Bochum, Germany

来源：

CURRENT OPINION IN ELECTROCHEMISTRY | 2018年 / 10卷

关键词：

CELLOBIOSE DEHYDROGENASE; MONITORING-SYSTEM; SENSORS; PERFORMANCE; ACCURACY; ELECTRODES; STABILITY; POLYMERS; OXIDASE;

D O I：

10.1016/j.coelec.2018.05.004

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Long-term implantable glucose sensors with a demonstrated lifetime of at least two weeks play a key role in continuous glucose monitoring (CGM) and the development of closed-loop artificial pancreas systems for the emerging number of diabetes patients. This short review summarises the current state of the art of CGM systems and points out specific limitations of amperometric glucose biosensors regarding their inherent sensor long-term and signal stability that are mainly caused by the inevitable foreign body response after sensor implantation.

引用

页码：112 / 119

页数：8

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