Electrospun nanofibrous biodegradable polyester coatings on Bioglass®-based glass-ceramics for tissue engineering

被引：33
|
作者：
Bretcanu, Oana [1 ]
Misra, Superb K. [1 ]
Yunos, D. Mohammad [1 ]
Boccaccini, Aldo R. [1 ]
Roy, Ipsita [2 ]
Kowalczyk, Tomasz [3 ]
Blonski, Slawomir [3 ]
Kowalewski, Tomasz A. [3 ]
机构：
[1] Univ London Imperial Coll Sci Technol & Med, Dept Mat, London, England
[2] Univ Westminster, Dept Mol & Appl Biosci, London W1R 8AL, England
[3] Polish Acad Sci IPPT PAN, Inst Fundamental Technol Res, Warsaw, Poland
来源：
MATERIALS CHEMISTRY AND PHYSICS | 2009年 / 118卷 / 2-3期
关键词：
Electrospinning; Nanofibers; Bioglass (R); Polyhydroxyalkanoates; Tissue engineering; BIOACTIVE GLASS; SCAFFOLDS; BONE; COMPOSITES; POLYMER; NANOTUBES; FOAMS;
D O I：
10.1016/j.matchemphys.2009.08.011
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Biodegradable polymeric nanofibrous coatings were obtained by electrospinning different polymer onto sintered 45S5 Bioglass (R)-based glass-ceramic pellets. The investigated polymers were (polyhydroxybutyrate) (P3HB), poly(3-hydroxybutyrate-co-hydroxyvalerate) (PHBV) and a composite poly(caprolactone) (PCL) and poly(ethylene oxide) (PEO) (PCL-PEO). The fibrous coatings morphology was evaluated by optical microscopy and scanning electron microscopy. The electrospinning pro parameters were optimised to obtain reproducible coatings formed by a thin web of polymer nanofit In-vitro studies in simulated body fluid (SBF) were performed to investigate the bioactivity and minimisation of the substrates by inducing the formation of hydroxyapatite (HA) on the nano fiber-coated HA crystals were detected on all samples after 7 days of immersion in SBF, however the morphology the HA layer depended on the characteristic fibre diameter, which in turn was a function of the specific polymer-solvent system used. The bioactive and resorbable nanofibrous coatings can be used to the the surface topography of bioactive glass-ceramics for applications in tissue engineering scaffolds. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码：420 / 426
页数：7
相关论文
共 50 条
  • [1] Electrospun biodegradable nanofibrous mats for tissue engineering
    Ndreu, Albana
    Nikkola, Lila
    Ylikauppila, Hanna
    Ashammakhi, Nureddin
    Hasirci, Vasif
    NANOMEDICINE, 2008, 3 (01) : 45 - 60
  • [2] Electrospun poly(d,l-lactide)/gelatin/glass-ceramics tricomponent nanofibrous scaffold for bone tissue engineering
    Bochicchio, Brigida
    Barbaro, Katia
    De Bonis, Angela
    Rau, Julietta, V
    Pepe, Antonietta
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2020, 108 (05) : 1064 - 1076
  • [3] Engineering controllable anisotropy in electrospun biodegradable nanofibrous scaffolds for musculoskeletal tissue engineering
    Li, Wan-Ju
    Mauck, Robert L.
    Cooper, James A.
    Yuan, Xiaoning
    Tuan, Rocky S.
    JOURNAL OF BIOMECHANICS, 2007, 40 (08) : 1686 - 1693
  • [4] Friction behavior of biodegradable electrospun polyester nanofibrous membranes
    Wang, Yi
    Zhai, Weijie
    Li, Junhan
    Liu, Haotian
    Li, Chong
    Li, Jinghua
    TRIBOLOGY INTERNATIONAL, 2023, 188
  • [5] Glass-ceramics as coatings for prostheses
    Dubini, B
    Krajewski, A
    Mazzocchi, M
    Bossi, MGP
    Ravaglioli, A
    Rizzi, G
    Rustichelli, F
    Stanic, V
    Giardino, R
    Nicoli-Aldini, N
    Verné, E
    Brovarone, CV
    BIOCERAMICS, 2000, 192-1 : 279 - 282
  • [6] A new scaffold for bone tissue engineering based in mesenchynal stem cells and glass-ceramics
    Meseguer Olmo, L.
    Garcia de Insausti, C.
    Bernabeu Esclapez, A.
    Rodriguez Lozano, F. J.
    Vallet Regi, M.
    Blanquer, M.
    Moraleda, J. M.
    Clavel, M.
    BONE MARROW TRANSPLANTATION, 2009, 43 : S192 - S193
  • [7] Composite Fiber Networks Based on Polycaprolactone and Bioactive Glass-Ceramics for Tissue Engineering Applications
    Jinga, Sorin-Ion
    Costea, Claudiu-Constantin
    Zamfirescu, Andreea-Ioana
    Banciu, Adela
    Banciu, Daniel-Dumitru
    Busuioc, Cristina
    POLYMERS, 2020, 12 (08)
  • [8] Bioactive glass-ceramics coatings on alumina
    Vitale Brovarone, C.
    Verné, E.
    Lupo, F.
    Moisescu, C.
    Zanardi, L.
    Bosetti, M.
    Cannas, M.
    Key Engineering Materials, 2001, 192-195 : 123 - 126
  • [9] Bioactive glass-ceramics coatings on alumina
    Brovarone, CV
    Verné, E
    Lupo, F
    Moisescu, C
    Zanardi, L
    Bosetti, M
    Cannas, M
    BIOCERAMICS, 2000, 192-1 : 123 - 126
  • [10] Bioactive glass-ceramics coatings on alumina
    Brovarone, C. Vitale
    Verne, E.
    Lupo, F.
    Moisescu, C.
    Zanardi, L.
    Bosetti, M.
    Cannas, M.
    Key Engineering Materials, 2001, 192-195 : 123 - 126
12345