Cellular retinoic acid-binding protein II: A coactivator of the transactivation by the retinoic acid receptor complex RAR.RXR

被引：0

作者：

Wolf, G ^{[1
]}

机构：

[1] Nutr Reviews Editorial Off, Boston, MA 02111 USA

来源：

NUTRITION REVIEWS | 2000年 / 58卷 / 05期

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D O I：

暂无

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Cellular retinoic acid-binding protein (CRABP) appears in vertebrate organisms in two isoforms, CRABPI and II, with distinct distribution and functions. CRABPII, when combined with its retinoic acid (RA) ligand, interacts specifically with the liganded RA receptor complex (RAR.RXR), which is bound to the RA response elements of particular genes in order to greatly activate their expression. Thus, liganded CRABPII acts as a coactivator for RAR. RXR.

引用

页码：151 / 153

页数：3

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