Sequential immunization with a subtype B HIV-1 envelope quasispecies elicits broader neutralization than vaccination with a single envelope clone

被引：0
|
作者：
Malherbe, D. C. [1 ]
Doria-Rose, N. [2 ]
Misher, L. [3 ]
Beckett, T. [3 ]
Blay-Puryear, W. [4 ]
Barnett, S. [5 ]
Srivastava, I. [5 ]
Richardson, B. [6 ]
Stamatatos, L. [7 ]
Haigwood, N. L. [1 ]
机构：
[1] Oregon Hlth & Sci Univ, Beaverton, OR USA
[2] NIH, Bethesda, MD 20892 USA
[3] Trub Pharmaceut, Seattle, WA USA
[4] Boston Univ, Boston, MA 02215 USA
[5] Novartis Vaccines & Diagnost, Cambridge, MA USA
[6] Univ Washington, Seattle, WA 98195 USA
[7] Seattle Biomed Res Inst, Seattle, WA 98109 USA
来源：
RETROVIROLOGY | 2009年 / 6卷
关键词：
Sequential Group; Viral Quasispecies; Protein Boost; Quasispecies Variant; Broad Neutralization;
D O I：
10.1186/1742-4690-6-S3-P86
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
引用
收藏
页数：2
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