Anti-TNF-α for Necrotizing Sarcoid Granulomatosis of the Liver

被引:11
|
作者
Sebode, Marcial [1 ]
Weidemann, Soeren [2 ]
Wehmeyer, Malte [1 ]
Lohse, Ansgar W. [1 ]
Schramm, Christoph [1 ]
机构
[1] Univ Med Ctr Hamburg Eppendorf, Dept Med 1, Martinistr 52, D-20246 Hamburg, Germany
[2] Univ Med Ctr Hamburg Eppendorf, Dept Pathol, Hamburg, Germany
关键词
D O I
10.1002/hep.28966
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
We present a case of hepatosplenic necrotizing sarcoid granulomatosis, a variant form of “classical” sarcoidosis, that became clinically apparent in the form of multiple hepatic and splenic masses mimicking malignancy. Flow cytometry of intrahepatic T cells isolated from liver biopsy led to the targeted treatment with anti-tumor necrosis factor-alpha, which was highly effective in inducing remission. (Hepatology 2017;65:1410-1412). © 2016 by the American Association for the Study of Liver Diseases
引用
收藏
页码:1410 / 1412
页数:3
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