Liposomal Daunorubicin (Daunoxome) provides increased intracellular drug accumulation in PGP overexpressing leukemic blast cells.

被引：0

作者：

Michieli, M

Damiani, D

Michelutti, A

Ermacora, A

Masolini, P

Pea, F

Baccarani, M

Fanin, R

机构：

[1] UNIV UDINE,DEPT CLIN & EXPT PATHOL,CHAIR PHARMACOL,I-33100 UDINE,ITALY

[2] UNIV HOSP,DEPT CLIN & MORPHOL RES,DIV HEMATOL,UDINE,ITALY

来源：

BLOOD | 1997年 / 90卷 / 10期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1472 / 1472

页数：1

共 14 条

[1] Anthacyclines for MDR leukemic patients: The liposome-encapsulated daunorubicin, daunoxome increases daunorubicin (DNR) cells killing in PGP overexpressing cases.
Michieli, M
Damiani, D
Masolini, P
Ermacora, A
Michelutti, A
Geromin, A
Baccarani, M
CLINICAL CANCER RESEARCH, 2000, 6 : 4503S - 4503S
[2] Liposomal daunorubicin (daunoxome(R)) is cytotoxic to childhood acute lymphoblastic leukemia cells.
Baruchel, A
Ito, C
Robert, J
Campana, D
BLOOD, 1997, 90 (10) : 3633 - 3633
[3] Liposomal daunorubicin (Daunoxome) results in higher plasma concentrations but similar intracellular concentrations in leukemic cells compared to non-encapsulated daunorubicin during induction treatment in acute myeloid leukemia (AML).
Lehmann, S
Bengtzen, S
Tidefelt, U
Lofgren, C
Mollgard, L
Paul, C
BLOOD, 2003, 102 (11) : 255B - 255B
[4] EFFECTS OF VERAPAMIL ON THE CELLULAR ACCUMULATION OF DAUNORUBICIN IN BLAST CELLS AND ON THE CHEMOSENSITIVITY OF LEUKEMIC BLAST PROGENITORS IN ACUTE MYELOGENOUS LEUKEMIA
MARUYAMA, Y
MUROHASHI, I
NARA, N
AOKI, N
BRITISH JOURNAL OF HAEMATOLOGY, 1989, 72 (03) : 357 - 362
[5] SATURATION OF INTRACELLULAR CYTOSINE-ARABINOSIDE TRIPHOSPHATE ACCUMULATION IN HUMAN LEUKEMIC BLAST CELLS
JAMIESON, GP
SNOOK, MB
WILEY, JS
LEUKEMIA RESEARCH, 1990, 14 (05) : 475 - 479
[6] EXPRESSION OF A 95-KDA MEMBRANE-PROTEIN IS ASSOCIATED WITH LOW DAUNORUBICIN ACCUMULATION IN LEUKEMIC BLAST CELLS
DOYLE, LA
ROSS, DD
SRIDHARA, R
FOJO, AT
KAUFMANN, SH
LEE, EJ
SCHIFFER, CA
BRITISH JOURNAL OF CANCER, 1995, 71 (01) : 52 - 58
[7] EFFECTS OF VERAPAMIL ON INVITRO INTRACELLULAR ACCUMULATION AND RETENTION OF DAUNORUBICIN IN BLAST CELLS FROM PATIENTS WITH ACUTE NONLYMPHOCYTIC LEUKEMIA
ROSS, DD
JONECKIS, CC
SCHIFFER, CA
BLOOD, 1986, 68 (01) : 83 - 88
[8] INTRACELLULAR CYTOSINE-ARABINOSIDE ACCUMULATION AND CYTOSINE-ARABINOSIDE TRIPHOSPHATE FORMATION IN LEUKEMIC BLAST CELLS IS INHIBITED BY ETOPOSIDE AND TENIPOSIDE
EHNINGER, G
PROKSCH, B
WANNER, T
SCHULER, U
BUSCH, FW
SCHMIDT, H
SCHLEYER, E
JASCHONEK, K
HIDDEMANN, W
LEUKEMIA, 1992, 6 (06) : 582 - 587
[9] EFFECTS OF CYCLOSPORINE-A AND VERAPAMIL ON THE INTRACELLULAR DAUNORUBICIN ACCUMULATION IN CHINESE-HAMSTER OVARY CELLS WITH INCREASING LEVELS OF DRUG-RESISTANCE
SILBERMANN, MH
BOERSMA, AWM
JANSSEN, ALW
SCHEPER, RJ
HERWEIJER, H
NOOTER, K
INTERNATIONAL JOURNAL OF CANCER, 1989, 44 (04) : 722 - 726
[10] Overexpression of multidrug resistance related protein (MRP) in acute myeloid leukaemia (AML) blast cells is associated with decreased intracellular daunorubicin accumulation (IDA) and predicts poor treatment outcome.
Borg, AG
Green, LM
Burgess, R
Yin, JAL
BLOOD, 1996, 88 (10) : 1429 - 1429

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