Palladium-catalyzed α-arylation of N-protected 2-piperidinones

被引：21
|
作者：
de Filippis, A [1 ]
Pardo, DG [1 ]
Cossy, J [1 ]
机构：
[1] ESPCI, CNRS, Lab Chim Organ Assoc, F-75231 Paris 05, France
来源：
TETRAHEDRON | 2004年 / 60卷 / 43期
关键词：
arylations lactams; palladium; zinc; coupling;
D O I：
10.1016/j.tet.2004.06.152
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A very simple method for obtaining alpha-arylated N-protected 2-piperidinones in high yield is described. The use of ZnCl2 and Pd(dba)(2) and the nature of the base are the key factors. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：9757 / 9767
页数：11
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