Herpes Zoster and Recurrent Herpes Zoster

被引:44
|
作者
Shiraki, Kimiyasu [1 ]
Toyama, Nozomu [2 ]
Daikoku, Tohru [1 ,3 ]
Yajima, Misako [1 ,4 ]
机构
[1] Univ Toyama, Dept Virol, Grad Sch Med & Pharmaceut Sci, Toyama, Japan
[2] Toyama Dermatol Clin, Nichinan City, Miyazaki, Japan
[3] Hokuriku Univ, Fac Pharmaceut Sci, Dept Microbiol, Kanazawa, Ishikawa, Japan
[4] EVEC Inc, Sapporo, Hokkaido, Japan
来源
OPEN FORUM INFECTIOUS DISEASES | 2017年 / 4卷 / 01期
关键词
epidemiology; herpes zoster; recurrence; varicella-zoster virus; POSTHERPETIC NEURALGIA; NATURAL-HISTORY; VARICELLA; VACCINE; RISK; VIRUS;
D O I
10.1093/ofid/ofx007
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background. The incidence of recurrent herpes zoster (HZ) and the relationship between initial and recurrent HZ are not clear. Methods. The Miyazaki Dermatologist Society has surveyed similar to 5000 patients with HZ annually since 1997. A questionnaire regarding HZ and its recurrence was completed by the dermatologists. Results. A total of 34 877 patients with HZ were registered at 43 clinics between June 2009 and November 2015. Among 16 784 patients seen at 10 of the 43 clinics, 1076 patients (6.41%) experienced recurrence. Herpes zoster was more frequent in female than in male patients (5.27 vs 4.25 in 1000 person-years, P <.001), as was HZ recurrence (7.63% vs 4.73%, P <.001). Two and three recurrences were observed in 49 and 3 patients, respectively. Recurrence in the same dermatome was observed in 16.3% of patients, and more frequently this occurred in the left side (P = .027). The number of HZ-experienced persons increased with age, and one third of the population had experienced HZ by the age of 80. Conclusions. Recurrent HZ was observed in 6.41% of patients, with a higher incidence in women. Moreover, HZ experience reduced the HZ incidence to 31.7% of the incidence in the HZ-naive population.
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页数:9
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