Anti-influenza virus activity of biflavonoids

被引：90
|
作者：
Miki, Kazuhiko
Nagai, Takayuki
Suzuki, Kazushige
Tsujimura, Ryo
Koyama, Kiyotaka
Kinoshita, Kaoru
Furuhata, Kimio
Yamada, Haruki
Takahashi, Kunio
机构：
[1] Meiji Pharmaceut Univ, Tokyo 2048588, Japan
[2] Kitasato Inst Life Sci, Minato Ku, Tokyo 1088641, Japan
[3] Kitasato Univ, Grad Sch Infect Control Sci, Minato Ku, Tokyo 1088641, Japan
[4] Kitasato Univ, Oriental Med Res Ctr, Minato Ku, Tokyo 1088642, Japan
[5] Kitasato Univ, Sch Pharm, Minato Ku, Tokyo 1088641, Japan
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2007年 / 17卷 / 03期
关键词：
influenza; ginkgetin; sialic acid; Ginkgo biloba; biflavonoid; sialidase;
D O I：
10.1016/j.bmcl.2006.10.075
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Ginkgetin was found to inhibit the influenza virus sialidase. Ginkgetin-sialic acid conjugates showed a significant survival effect in the influenza-virus-infected mice. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：772 / 775
页数：4
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