Synthesis and antimicrobial activity of pyridine derivatives substituted at C-2 and C-6 positions

被引：0
|
作者：
De Almeida, Mauro Vieira [1 ]
de Nora Souza, Marcus Vinicius
Barbosa, Nadia Rezende
Silva, Frederico Pittella
Amarante, Giovanni Wilson
Cardoso, Silvia Helena
机构：
[1] Univ Fed Juiz de Fora, ICE, Dept Quim, BR-36036330 Juiz De Fora, MG, Brazil
[2] Univ Fed Juiz de Fora, Fac Farm & Bioquim, BR-36036330 Juiz De Fora, MG, Brazil
来源：
LETTERS IN DRUG DESIGN & DISCOVERY | 2007年 / 4卷 / 02期
关键词：
substituted pyridines; amide; antimicrobial activity; synthesis;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A series of C-2 and C-6 substituted pyridines was synthesized and evaluated in vitro against Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus mutans and Candida albicans. Most of compounds exhibited a wide range of modest in vitro activity against the tested microorganisms.
引用
收藏
页码：149 / 153
页数：5
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