Interleukin-2 production by human pre-implantation embryos

被引:0
|
作者
Orvieto, R
BarHava, I
Schwartz, A
Shelef, M
BenRafael, Z
机构
关键词
interleukin-2; pre-implantation embryos; in vitro fertilization;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The study was conducted to determine whether preimplantation embryos secrete interleukin-2. Conditioned media of 27 embryos derived from women during in vitro fertilization (IVF) cycles were analyzed for interleukin-2 concentration. The results showed that conditioned embryo medium from the two pronuclei stage to 24 hours later contains interleukin-2. Endometrial large granular lymphocytes, which are probably involved in placentation, replicate in response to interleukin-2. It may therefore be speculated that interleukin-2 secreted by human embryos may modulate the function and replication of large granular lymphocytes.
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页码:331 / 334
页数:4
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