The importance of genome sequence quality to microbial comparative genomics

被引:37
|
作者
Smits, Theo H. M. [1 ]
机构
[1] Zurich Univ Appl Sci ZHAW, Environm Genom & Syst Biol Res Grp, Inst Nat Resource Sci IUNR, Wadenswil, Switzerland
关键词
Assembly; Taxonomy; Genomes; Sequencing; Annotations; FAMILY; MAUVE;
D O I
10.1186/s12864-019-6014-5
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The quality of microbial genome sequences has been a concern ever since the emergence of genome sequencing. The quality of the genome assemblies is dependent on the sequencing technology used and the aims for which the sequence was generated. Novel sequencing and bioinformatics technologies are not intrinsically better than the older technologies, although they are generally more efficient. In this correspondence, the importance for comparative genomics of additional manual assembly efforts over autoassembly and careful annotation is emphasized.
引用
下载
收藏
页数:4
相关论文
共 50 条
  • [1] The importance of genome sequence quality to microbial comparative genomics
    Theo H. M. Smits
    BMC Genomics, 20
  • [2] Microbial genomics - Genome sequence of an extreme halophile
    Pallen, M
    TRENDS IN MICROBIOLOGY, 2001, 9 (02) : 58 - 58
  • [3] Microbial genomics -: Caulobacter crescentus genome sequence
    Pallen, M
    TRENDS IN MICROBIOLOGY, 2001, 9 (05) : 201 - 201
  • [4] Genome sequence and comparative genomics of Pseudomonas savastanoi
    Qi, M.
    Wang, D.
    Bradley, C. A.
    Zhao, Y.
    PHYTOPATHOLOGY, 2010, 100 (06) : S104 - S105
  • [5] MicroScope: a platform for microbial genome annotation and comparative genomics
    Vallenet, D.
    Engelen, S.
    Mornico, D.
    Cruveiller, S.
    Fleury, L.
    Lajus, A.
    Rouy, Z.
    Roche, D.
    Salvignol, G.
    Scarpelli, C.
    Medigue, C.
    DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION, 2009,
  • [6] The genome sequence of Caenorhabditis briggsae:: A platform for comparative genomics
    Stein, LD
    Bao, ZR
    Blasiar, D
    Blumenthal, T
    Brent, MR
    Chen, NS
    Chinwalla, A
    Clarke, L
    Clee, C
    Coghlan, A
    Coulson, A
    D'Eustachio, P
    Fitch, DHA
    Fulton, LA
    Fulton, RE
    Griffiths-Jones, S
    Harris, TW
    Hillier, LW
    Kamath, R
    Kuwabara, PE
    Mardis, ER
    Marra, MA
    Miner, TL
    Minx, P
    Mullikin, JC
    Plumb, RW
    Rogers, J
    Schein, JE
    Sohrmann, M
    Spieth, J
    Stajich, JE
    Wei, CC
    Willey, D
    Wilson, RK
    Durbin, R
    Waterston, RH
    PLOS BIOLOGY, 2003, 1 (02) : 166 - +
  • [7] Using comparative genomics to reorder the human genome sequence into a virtual sheep genome
    Brian P Dalrymple
    Ewen F Kirkness
    Mikhail Nefedov
    Sean McWilliam
    Abhirami Ratnakumar
    Wes Barris
    Shaying Zhao
    Jyoti Shetty
    Jillian F Maddox
    Margaret O'Grady
    Frank Nicholas
    Allan M Crawford
    Tim Smith
    Pieter J de Jong
    John McEwan
    V Hutton Oddy
    Noelle E Cockett
    Genome Biology, 8
  • [8] Using comparative genomics to reorder the human genome sequence into a virtual sheep genome
    Dalrymple, Brian P.
    Kirkness, Ewen F.
    Nefedov, Mikhail
    McWilliam, Sean
    Ratnakumar, Abhirami
    Barris, Wes
    Zhao, Shaying
    Shetty, Jyoti
    Maddox, Jillian F.
    O'Grady, Margaret
    Nicholas, Frank
    Crawford, Allan M.
    Smith, Tim
    de Jong, Pieter J.
    McEwan, John
    Oddy, V. Hutton
    Cockett, Noelle E.
    GENOME BIOLOGY, 2007, 8 (07)
  • [9] Leveraging the rice genome sequence for monocot comparative and translational genomics
    H. C. Lohithaswa
    F. A. Feltus
    H. P. Singh
    C. D. Bacon
    C. D. Bailey
    A. H. Paterson
    Theoretical and Applied Genetics, 2007, 115 : 237 - 243
  • [10] Complete genome sequence of an archaeon: A first chance for comparative genomics
    Denamur, E
    M S-MEDECINE SCIENCES, 1997, 13 (01): : 81 - 82