Infections in systemic connective tissue diseases:: Systemic lupus erythematosus, scleroderma, and polymyositis/dermatomyositis

被引:55
|
作者
Alarcon, Graciela S. [1 ]
机构
[1] Univ Alabama Birmingham, Div Clin Immunol & Rheumatol, Dept Med, Birmingham, AL 35294 USA
关键词
D O I
10.1016/j.idc.2006.09.007
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Systemic lupus erythematosus (SLE), scleroderma, and polymyositis/dermatomyositis (PM/DM) are autoimmune diseases with high morbidity and mortality. The important role infections play in these diseases has been documented in the literature over the years. This article reviews the role of infections in these three disorders, emphasizing in each (1) the predisposing factors for the development of infections, (2) the effect of infections on mortality, and (3) the most common microorganisms involved in these infectious processes.
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页码:849 / +
页数:28
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