Ultrasound-triggered smart drug release from a poly(dimethylsiloxane)-mesoporous silica composite

被引:214
|
作者
Kim, Hyun-Jong [1 ]
Matsuda, Hirofumi [1 ]
Zhou, Haoshen [1 ]
Honma, Itaru [1 ]
机构
[1] Natl Inst Adv Ind Sci & Technol, Energy Technol Res Inst, Nanoenergy Mat Grp, Tsukuba, Ibaraki 3058568, Japan
关键词
D O I
10.1002/adma.200600387
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Ultrasound is used as an external trigger for the pulsatile release of the drug ibuprofen. The system is composed of mesoporous silica as the drug reservoir and poly(dimethylsiloxane) (PDMS) as an implantable body. This system could find use for in vivo delivery of drugs in response to changes in physiological conditions.
引用
收藏
页码:3083 / +
页数:7
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