An efficient method for the synthesis of 2,4,5-trisubstituted imidazoles using lactic acid as promoter

被引：12
|
作者：
Sonar, Jayant [1 ]
Pardeshi, Sandeep [1 ]
Dokhe, Shrikant [1 ]
Pawar, Rajendra [4 ]
Kharat, Kiran [5 ]
Zine, Ashok [2 ]
Matsagar, Babasaheb [3 ]
Wu, Kevin [3 ]
Thore, Shivaji [4 ]
机构：
[1] Vinayakrao Patil Mahavidyalaya, Dept Chem, Aurangabad 423701, Maharashtra, India
[2] Sunderrao Solunke Mahavidyalaya, Dept Chem, Majalgaon 431131, Maharashtra, India
[3] Natl Taiwan Univ, Chem Engn Dept, Taipei 106, Taiwan
[4] Deogiri Coll, Dept Chem, Stn Rd, Aurangabad 431005, Maharashtra, India
[5] Deogiri Coll, Dept Biotechnol, Stn Rd, Aurangabad 431005, Maharashtra, India
来源：
SN APPLIED SCIENCES | 2019年 / 1卷 / 09期
关键词：
Lactic acid; Promotor; Green solvent; 2,4,5-Trisubstituted imidazoles; DERIVATIVES; CATALYST;
D O I：
10.1007/s42452-019-0935-0
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Synthesis of 2,4,5-trisubstituted imidazole compounds from an aromatic aldehyde, benzil and ammonium acetate is demonstrated using biodegradable lactic acid at 160 degrees C. This method is a simple, environmentally benign, and works for aromatic aldehyde containing electron donating and electron withdrawing groups. [GRAPHICS] .
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页数：7
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