Potential cytotoxic activity of some Brazilian seaweeds on human melanoma cells

被引：45
|
作者：
Rocha, Fabiola Dutra [1 ]
Soares, Angelica Ribeiro
Houghton, Peter John
Pereira, Renato Crespo
Coelho Kaplan, Maria Auxiliadora
Teixeira, Valeria Laneuville
机构：
[1] Univ Fed Rio de Janeiro, Programa Posgrad Prod Nat Nucl Pesquisas Prod Nat, BR-21941590 Rio De Janeiro, Brazil
[2] NUPESC, Fdn UNIRG, BR-77410100 Gurupi, TO, Brazil
[3] Univ Fed Fluminense, Inst Quim, Programa Posgrad Quim Organ, BR-24001970 Niteroi, RJ, Brazil
[4] Kings Coll London, Dept Pharm, London SE1 8WA, England
[5] Univ Fed Fluminense, Dept Biol Marinha, Inst Biol, BR-24001970 Niteroi, RJ, Brazil
来源：
PHYTOTHERAPY RESEARCH | 2007年 / 21卷 / 02期
关键词：
Brazilian seaweeds; cytotoxicity; melanoma; anticancer;
D O I：
10.1002/ptr.2038
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
In vitro screening of the crude extracts of some Brazilian coastal seaweeds for cytotoxic activity against a cultured human melanoma cancer cell line using the sulphorhodamine B assay was performed. The crude dichloromethane:chloroform extract of Stypopodium zonale showed good cytotoxic activity against the C32 cell line. The crude acetone extract and aqueous phase of Lobophora variegata did not show any activity, but semi-purified fractions XAD LOB I and Il could inhibit the growth of melanoma cells. The crude acetone extract of Caulerpa racemosa showed some cytotoxicity, but caulerpin isolated from this extract did not show any such activity. The crude acetone extract of Spatoglossum schroederi was not able to inhibit the growth of C32 melanoma cells. Copyright (c) 2006 John Wiley & Sons, Ltd.
引用
收藏
页码：170 / 175
页数：6
相关论文
共 50 条
  • [1] Potential Cytotoxic Activity of Galegine on Human Melanoma Cells
    Arjmand, Mohammad Hassan
    Sabri, Hamed
    Maghrouni, Abolfazl
    Zarei, Elmira
    Hotelchi, Massoumeh
    Afshari, Amir Reza
    RESEARCH JOURNAL OF PHARMACOGNOSY, 2022, 9 (03) : 15 - 23
  • [2] Evaluation of the Cytotoxic Activity of Some Brazilian Medicinal Plants
    Ribeiro, Sandra S.
    de Jesus, Aline M.
    dos Anjos, Charlene S.
    da Silva, Thanany B.
    Santos, Alan D. C.
    de Jesus, Jemmyson R.
    Andrade, Moacir S.
    Sampaio, Tais S.
    Gomes, Wesley F.
    Alves, Pericles B.
    Carvalho, Adriana A.
    Pessoa, Claudia
    de Moraes, Manoel O.
    Pinheiro, Maria L. B.
    Prata, Ana Paula N.
    Blank, Arie F.
    Silva-Mann, Renata
    Moraes, Valeria R. S.
    Costa, Emmanoel V.
    Nogueira, Paulo Cesar L.
    Bezerra, Daniel P.
    PLANTA MEDICA, 2012, 78 (14) : 1601 - 1606
  • [3] The cytotoxic activity of sanguinarine in C32 human amelanotic melanoma cells
    Cojocaru, Sabina Ioana
    Stan, Miruna Silvia
    Anton, Mihai
    Luca, Mihaela Rocsana
    Ghiorghita, Gogu
    Stoian, Gheorghe
    Dinischiotu, Anca
    TURKISH JOURNAL OF BIOLOGY, 2016, 40 (01) : 130 - 138
  • [4] DEMONSTRATION OF ANTIBODY IN MELANOMA PATIENTS CYTOTOXIC TO HUMAN MELANOMA CELLS
    GRAY, BK
    MEHIGAN, JT
    MORTON, DL
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1971, 12 (NMAR): : 79 - &
  • [5] Determination of Cytotoxic Activity of Sanguinaria canadensis Extracts against Human Melanoma Cells and Comparison of Their Cytotoxicity with Cytotoxicity of Some Anticancer Drugs
    Tuzimski, Tomasz
    Petruczynik, Anna
    Plech, Tomasz
    Kapron, Barbara
    Makuch-Kocka, Anna
    Szultka-Mlynska, Malgorzata
    Misiurek, Justyna
    Buszewski, Boguslaw
    MOLECULES, 2021, 26 (06):
  • [6] Inhibition on Telomerase Activity and Cytotoxic Effects by Cisplatin in Cultured Human Choroidal Melanoma Cells
    Hao Cheng Zhongyao Wu Jianliang Zheng Guilan Lu Jianhua Yan Min Liu Danping Huang Jianxian LinZhongshan Ophthalmic Center Sun Yatsen University Guangzhou China
    眼科学报, 2003, (01) : 54 - 59
  • [7] Cytotoxic Activity of Oleocanthal Isolated from Virgin Olive Oil on Human Melanoma Cells
    Fogli, Stefano
    Arena, Chiara
    Carpi, Sara
    Polini, Beatrice
    Bertini, Simone
    Digiacomo, Maria
    Gado, Francesca
    Saba, Alessandro
    Saccomanni, Giuseppe
    Breschi, Maria Cristina
    Nieri, Paola
    Manera, Clementina
    Macchia, Marco
    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2016, 68 (05): : 873 - 877
  • [8] In vitro potential activity of some seaweeds as antioxidants and inhibitors of diabetic enzymes
    Ismail, Gehan Ahmed
    Gheda, Saly Farouk
    Abo-shady, Atef Mohamed
    Abdel-karim, Omnia Hamdy
    FOOD SCIENCE AND TECHNOLOGY, 2020, 40 (03): : 681 - 691
  • [9] Synthesis and Cytotoxic Evaluation of Kojic Acid Derivatives with Inhibitory Activity on Melanogenesis in Human Melanoma Cells
    Karakaya, Gulsah
    Ercan, Ayse
    Oncul, Selin
    Aytemir, Mutlu D.
    ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2018, 18 (15) : 2137 - 2148
  • [10] A new ceramide from Suillus luteus and its cytotoxic activity against human melanoma cells
    Leon, Francisco
    Brouard, Ignacio
    Torres, Fernando
    Quintana, Jose
    Rivera, Augusto
    Estevez, Francisco
    Bermejo, Jaime
    CHEMISTRY & BIODIVERSITY, 2008, 5 (01) : 120 - 125
12345