Nursing home-acquired pneumonia

被引:104
|
作者
Mylotte, JM
机构
[1] Erie Cty Med Ctr & Labs, Dept Med, Buffalo, NY 14215 USA
[2] SUNY Buffalo, Sch Med & Biomed Sci, Dept Microbiol, Buffalo, NY USA
[3] SUNY Buffalo, Dept Med, Div Infect Dis, Buffalo, NY USA
关键词
D O I
10.1086/344281
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Pneumonia is the most serious of the common infections that occur in nursing homes, with a high case-fatality rate and considerable mortality among survivors. Risk factors for nursing home-acquired pneumonia (NHAP) have been defined, and prediction models for death due to NHAP have been developed. The bacterial etiology of NHAP has been debated, but "typical" bacterial pathogens (Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis) are most important. Clinical presentation of NHAP is said to be "atypical," but this may be confounded by dementia in the nursing home resident. A recent guideline has made recommendations regarding the minimal diagnostic workup when a resident has a suspected case of pneumonia. Until recently, most guidelines for the treatment of pneumonia did not specifically address NHAP; there is some evidence that use of a quinolone alone may be an acceptable first choice of therapy for most cases. Pneumococcal and influenza vaccination have been the primary prevention measures. However, additional methods to prevent NHAP should be evaluated, including improving the oral hygiene of residents and instituting pharmacological interventions.
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页码:1205 / 1211
页数:7
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