Palladium-catalyzed amination of 3-bromo-4-fluoro-acetophenone

被引：6
|
作者：
Sun, LQ [1 ]
He, H [1 ]
Chen, J [1 ]
Wu, YJ [1 ]
机构：
[1] Bristol Myers Squibb Co, Pharmaceut Res Inst, Wallingford, CT 06492 USA
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 51期
关键词：
D O I：
10.1016/S0040-4039(02)02384-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The palladium-catalyzed amination of 3-bromo-4-fluoro-acetophenone was found to predominate over both the 4-fluoro nucleophilic substitution with amines and the palladium-catalyzed alpha-arylation of the acetyl group. (C) 2002 Elsevier Science Ltd. All rights reserved.
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收藏
页码：9291 / 9294
页数：4
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