Magnetization transfer and diffusion-weighted imaging in nocturnal frontal lobe epilepsy

被引:19
|
作者
Ferini-Strambi, L
Bozzali, M
Cercignani, M
Oldani, A
Zucconi, M
Filippi, M
机构
[1] Hosp San Raffaele, Inst Sci, Dept Neurosci, Neuroimaging Res Unit, I-20132 Milan, Italy
[2] Hosp San Raffaele, Inst Sci, Dept Neurosci, Sleep Disorders Ctr, I-20132 Milan, Italy
关键词
D O I
10.1212/WNL.54.12.2331
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors assessed the presence of brain abnormalities in 21 patients with nocturnal frontal lobe epilepsy (NFLE), using magnetization transfer ratio (MTR) and mean diffusivity ((D) over bar) histograms. Compared with healthy volunteers and patients with idiopathic generalized epilepsy, patients with NFLE had lower MTR (p = 0.002 and 0.01) and (D) over bar (p = 0.03 and 0.04) histogram peak heights. Subtle and widespread abnormalities related to intra- and extracellular distribution and motion of water are detectable in the brains of patients with NFLE.
引用
收藏
页码:2331 / 2333
页数:3
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