Nonequilibrium and Generalized-Ensemble Molecular Dynamics Simulations for Amyloid Fibril

被引：0
|
作者：
Okumura, Hisashi [1 ,2 ]
机构：
[1] Natl Inst Nat Sci, Inst Mol Sci, Res Ctr Computat Sci, 38 Nishigonaka, Okazaki, Aichi 4448585, Japan
[2] Grad Univ Adv Studies, Dept Struct Mol Sci, Okazaki, Aichi 4448585, Japan
来源：
INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2015 (ICCMSE 2015) | 2015年 / 1702卷
关键词：
Molecular dynamics; Amyloid fibril; Protein aggregation; REPLICA-PERMUTATION METHOD;
D O I：
10.1063/1.4938841
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
Amyloids are insoluble and misfolded fibrous protein aggregates and associated with more than 20 serious human diseases. We perform all-atom molecular dynamics simulations of amyloid fibril assembly and disassembly.
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页数：2
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