Physical Markov Model for Protein Structure Prediction

Popular protein folding simulations such as molecular dynamics (MD)-based simulations require large amounts of CPU time. Statistical- template and combined MID template simulations can be very accurate however often fail to provide physical insight into the physical processes of folding and mis-folding. The presented Markov simulation based on particle diffusion and drift via rotation angle is: fast, reasonably accurate, and provides essential insights. Solving many intermediate problems lead to these abilities.