Miniscrews in orthodontic treatment: Review and analysis of published clinical trials

Introduction: A systematic review of effects related to patient, screw, surgery, and loading on the stability of miniscrews was conducted. Methods: Reports of clinical trials published before September 2007 with at least 30 miniscrews were reviewed. Parameters examined were patient sex and age, location and method of screw placement, screw length and diameter, time, and amount of loading. Results: Fourteen clinical trials included 452 patients and 1519 screws. The mean overall success rate was 83.8% +/- 7.4%. Patient sex showed no significant differences. In terms of age, 1 of 5 studies with patients over 30 years of age showed a significant difference (P < 0.05). Screw diameters of 1 to 1.1 mm yielded significantly lower success rates than those of 1.5 to 2.3 mm. One study reported significantly lower success rates for 6-mm vs 8-mm long miniscrews (72% vs 90%). Screw placement with or without a surgical flap showed contradictory results between studies. Three studies showed significantly higher success rates for maxillary than for mandibular screws. Loading and healing period were not significant in the miniscrews' success rates. Conclusions: All 14 articles described success rates sufficient for orthodontic treatment. Placement protocols varied markedly. Screws under 8 mm in length and 1.2 mm in diameter should be avoided. Immediate or early loading up to 200 cN was adequate and showed no significant influence on screw stability. (Am J Orthod Dentofacial Orthop 2010; 137:108-13)