Even very low but sustained lithium intake can prevent suicide in the general population?

被引：17

作者：

Terao, Takeshi ^{[1
]}

Goto, Shinjiro ^{[1
]}

Inagaki, Masatoshi ^{[2
]}

Okamoto, Yasumasa ^{[3
]}

机构：

[1] Oita Univ, Dept Neuropsychiat, Fac Med, Oita 8795593, Japan

[2] Natl Ctr Neurol & Psychiat, NIMH, Ctr Suicide Prevent, Sect Med Res Suicide, Kodaira, Tokyo 1878553, Japan

[3] Hiroshima Univ, Dept Psychiat & Neurosci, Div Frontier Med Sci, Program Biomed Res,Grad Sch Biomed Sci, Hiroshima 7348551, Japan

来源：

MEDICAL HYPOTHESES | 2009年 / 73卷 / 05期

关键词：

BIPOLAR DISORDER; DRINKING-WATER; RISK; NEUROBIOLOGY; AGGRESSION; INCREASES; BEHAVIOR; RATES;

D O I：

10.1016/j.mehy.2009.02.043

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Although several meta-analyses have shown anti-suicidal properties of lithium in treating patients with mood disorders, these effects may be unrelated to the mood-stabilizing effects. Some epidemiological studies suggest that even very low lithium levels induced by routine consumption of lithium from tap water may have anti-suicidal effects both in patients with mood disorders and in the general population. We hypothesize that even very low but sustained lithium intake can prevent suicide in the general population. If this is the case, increasing lithium levels of drinking water could potentially reduce the risk of suicide, and justify administering lithium to tap water. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：811 / 812

页数：2

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