Attempted synthesis of casbene by intramolecular cyclopropanation

被引：11

作者：

Doyle, MP ^{[1
]}

Yan, M ^{[1
]}

机构：

[1] Univ Arizona, Dept Chem, Tucson, AZ 85721 USA

来源：

ARKIVOC | 2002年

关键词：

dirhodium(II) catalysis; vinyldiazomethane; copper(I) catalysis; diterpene; macrocyclization;

D O I：

10.3998/ark.5550190.0003.818

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The antifungal diterpene casbene has been prepared in low yield by intramolecular cyclopropanation of the vinyldiazomethane reactant formed from geranylgeraniol. Careful analysis of the reaction mixture revealed relatively unselective addition catalyzed by dirhodium(II) and copper(I) catalysts.

引用

页码：180 / 185

页数：6

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