Perspectives on the Application of Genome-Editing Technologies in Crop Breeding

被引：91

作者：

Hua, Kai ^{[1
]}

Zhang, Jinshan ^{[1
]}

Botella, Jose Ramon ^{[2
]}

Ma, Changle ^{[3
]}

Kong, Fanjiang ^{[4
]}

Liu, Baohui ^{[4
]}

Zhu, Jian-Kang ^{[1
,5
]}

机构：

[1] Chinese Acad Sci, CAS Ctr Excellence Mol Plant Sci, Shanghai Ctr Plant Stress Biol, Shanghai 200032, Peoples R China

[2] Univ Queensland, Sch Agr & Food Sci, Brisbane, Qld 4072, Australia

[3] Shandong Normal Univ, Sch Life Sci, Shandong Prov Key Lab Plant Stress, Jinan, Shandong, Peoples R China

[4] Guangzhou Univ, Sch Life Sci, Guangzhou, Guangdong, Peoples R China

[5] Purdue Univ, Dept Hort & Landscape Architecture, W Lafayette, IN 47907 USA

来源：

MOLECULAR PLANT | 2019年 / 12卷 / 08期

关键词：

genome editing; crop breeding; mutations; base editing; plants; HOMOLOGOUS RECOMBINATION; CRISPR-CAS9; NUCLEASES; QUANTITATIVE TRAITS; RAPID IMPROVEMENT; INDUCED MUTATIONS; TARGET BASE; GENE; DNA; PLANT; RICE;

D O I：

10.1016/j.molp.2019.06.009

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Most conventional and modern crop-improvement methods exploit natural or artificially induced genetic variations and require laborious characterization of the progenies of multiple generations derived from time-consuming genetic crosses. Genome-editing systems, in contrast, provide the means to rapidly modify genomes in a precise and predictable way, making it possible to introduce improvements directly into elite varieties. Here, we describe the range of applications available to agricultural researchers using existing genome-editing tools. In addition to providing examples of genome-editing applications in crop breeding, we discuss the technical and social challenges faced by breeders using genome-editing tools for crop improvement.

引用

页码：1047 / 1059

页数：13

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