Lethal factor to mice produced by Escherichia coli isolated from chickens with swollen head syndrome

被引：1

作者：

Salvadori, MR

Chudzinski-Tavassi, AM

Baccaro, MR

Ferreira, CSA

Ferreira, AJP

Prado-Franceschi, J

Yano, T ^{[1
]}

机构：

[1] Univ Estadual Campinas, Inst Biol, Dept Microbiol & Imunol, BR-13081970 Campinas, SP, Brazil

[2] Inst Butantan, Lab Bioquim & Biofis, BR-05503900 Sao Paulo, Brazil

[3] Univ Sao Paulo, Fac Vet Med & Zootecn, Dept Patol, BR-05508900 Sao Paulo, Brazil

[4] Univ Estadual Campinas, Fac Ciencias Med, Dept Farmacol, BR-13081970 Campinas, SP, Brazil

来源：

MICROBIOLOGY AND IMMUNOLOGY | 2002年 / 46卷 / 11期

关键词：

chickens; Escherichia coli; lethal factor; mice;

D O I：

10.1111/j.1348-0421.2002.tb02763.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A lethal toxin similar to Bacillus cererus lethal toxin was detected in the culture supernatants of Escherichia coli isolated from chickens with swollen head syndrome. The lethal activity was heat-labile, protease-sensitive and killed mice within 10 min. The. light microscopy of the histopathological studies revealed that the principal organ affected by this toxin was the lung but the liver and kidneys also showed lesions. The relevance of this lethal activity from E. coli remains to be determined.

引用

页码：773 / 775

页数：3

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