Lead poisoning from Ayurvedic treatment: a further case

被引:3
|
作者
Ciocan, Catalina [1 ,2 ]
Mansour, Ihab [1 ]
Beneduce, Alessandro [1 ]
Loia, Riccardo Corgiat [1 ]
Milanesio, Nicolo [1 ]
Declementi, Michael [1 ]
Godono, Alessandro [1 ]
Garzaro, Giacomo [1 ,2 ]
Pira, Enrico [1 ,2 ]
机构
[1] Univ Torino, Dept Publ Hlth & Pediat, Turin, Italy
[2] Citta Salute & Sci Torino Univ Hosp, Occupat Hlth Serv, Turin, Italy
来源
MEDICINA DEL LAVORO | 2021年 / 112卷 / 02期
关键词
Ayurvedic; lead poisoning; anaemia; chelation; drug safety; MEDICINE USE; TOXICITY; CHELATION;
D O I
10.23749/mdl.v112i2.10576
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Purpose: We report a case of a 30 years old Indian sailor with microcytic anemia (Hb 9.9), persistent abdominal pain, emesis, dark stool, hyperchromic urine, latent jaundice and asthenia. Lead intoxication was confirmed (blood lead value of 102 mu g/dL). The patient assumed Ayurvedic medicines in the previous months. Ayurveda is an ancient form of Indian traditional popular medicine aiming to re-establish health and body function through herbal preparations, heavy metals are often added. Our purpose was to treat the patient and to establish the source of poisoning. Methods: After testing blood and urine lead concentration of other 3 crew members and analyzing over than 150 products used on the ship professional exposure was excluded. We analyzed the two Ayurvedic drugs assumed by the patient with an Inductively Coupled Plasma Mass Spectrometry. The patient underwent three chelation cycles with Calcium Disodium Ethylenediaminetetraacetic acid (EDTA) while monitoring blood and urinary lead levels. Results: The final blood lead level at discharge, after three chelation cycles, was 36.27 mu g/dL. One of the two drugs contained extremely high concentrations of lead and mercury. The three different mixtures of this preparation showed lead concentrations of 12,638.54 mg/kg (Sample 2A), 23,043.02 mg/kg (Sample 2B), 21,352.97 mg/kg (Sample 2C); these levels are much higher than the highest values reported in literature for the indian soil (32 mg/kg). Conclusions: This case and similar cases raise the safety alert on complementary and alternative medicines; Ayurvedic medicine users should be carefully informed about potential risks and signs of poisoning.
引用
收藏
页码:162 / 166
页数:5
相关论文
共 50 条
  • [1] A paediatric case of lead poisoning from Ayurvedic medicine for the treatment of nail psoriasis
    Rajpopat, M.
    Robinson, J.
    Chow, Y.
    Dargan, P.
    O'Toole, E.
    BRITISH JOURNAL OF DERMATOLOGY, 2018, 179 : 73 - 73
  • [2] Lead poisoning from Ayurvedic medicines
    Tsutsui, Rayji S.
    Van Schalkwyk, Johan
    Spriggs, David
    NEW ZEALAND MEDICAL JOURNAL, 2013, 126 (1374) : 80 - 83
  • [3] Severe Lead Poisoning from Ayurvedic Remedy
    Scherbaum, C.
    Lemberg, K.
    Tappert, I.
    Frank, T.
    Hueser, C.
    Mueller, R-U
    Hackl, M.
    Burst, V.
    Suarez, V.
    MEDIZINISCHE KLINIK-INTENSIVMEDIZIN UND NOTFALLMEDIZIN, 2021, 116 (SUPPL 2) : 53 - 53
  • [4] Ayurvedic Remedy for Diabetes as a Cause of Lead Poisoning: A Case Report
    Desai, Amishi
    Staszewski, Harry
    AMERICAN JOURNAL OF MEDICINE, 2012, 125 (10): : E3 - E4
  • [5] A RARE CASE OF LEAD POISONING FROM AYURVEDIC MEDICATION IN AN ELDERLY PATIENT WITH PARKINSON DISEASE
    Pham, Nguyen V.
    Takimoto, Sarah W.
    Gryguc-Saxanoff, Agnieszka
    JOURNAL OF GENERAL INTERNAL MEDICINE, 2023, 38 : S418 - S419
  • [6] Lead Poisoning due to Ayurvedic Remedies
    Giampreti, A.
    Lonati, D.
    Vecchio, S.
    Petrolini, V
    Bigi, S.
    Bonetti, C.
    Locatelli, C.
    Manzo, L.
    CLINICAL TOXICOLOGY, 2009, 47 (05) : 478 - 479
  • [7] Ayurvedic herbal medicine and lead poisoning
    Krishna S Gunturu
    Priyadharsini Nagarajan
    Peter McPhedran
    Thomas R Goodman
    Michael E Hodsdon
    Matthew P Strout
    Journal of Hematology & Oncology, 4
  • [8] Ayurvedic herbal medicine and lead poisoning
    Gunturu, Krishna S.
    Nagarajan, Priyadharsini
    McPhedran, Peter
    Goodman, Thomas R.
    Hodsdon, Michael E.
    Strout, Matthew P.
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2011, 4
  • [9] Lead poisoning caused by Ayurvedic medicines
    Gitelman, Julian
    An, Howard
    Spilchuk, Vincent
    Kim, Jinhee
    CANADIAN MEDICAL ASSOCIATION JOURNAL, 2023, 195 (38) : E1326 - E1328
  • [10] Imported Ayurvedic Medicine and Lead Poisoning
    Horiuchi, Tomoaki
    Narimatsu, Kazuyuki
    Hokari, Ryota
    INTERNAL MEDICINE, 2022, 61 (21) : 3313 - 3313