Randomized Controlled Trials for the Treatment of Hidradenitis Suppurativa

被引：13
|
作者：
van Rappard, Dominique C. [1 ]
Mekkes, Jan R. [1 ]
Tzellos, Thrasivoulos [2 ]
机构：
[1] Univ Amsterdam, Acad Med Ctr, Dept Dermatol, NL-1105 AZ Amsterdam, Netherlands
[2] Univ Hosp North Norway, Fac Hlth Sci, Dept Dermatol, N-9407 Harstad, Troms, Norway
来源：
DERMATOLOGIC CLINICS | 2016年 / 34卷 / 01期
关键词：
Randomized controlled trials; Hidradenitis suppurativa; Treatment; Biologics; Surgery; Laser; Evidence based; Antibiotics; DOUBLE-BLIND; ADALIMUMAB; MODERATE; THERAPY;
D O I：
10.1016/j.det.2015.08.012
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Hidradenitis suppurativa (HS) is a chronic, inflammatory, recurrent, debilitating skin disease. Several treatment modalities are available, but most of them lack high-quality evidence. A systematic search was performed to identify all randomized controlled trials for the treatment of HS in order to review and evaluate the evidence. Recommendations for future randomized controlled trials include using validated scores, inclusion of patient rated outcomes, and thorough report of side effects. Evidence for long-term treatment and benefit/risk ratio of available treatment modalities is needed in order to enhance evidence-based treatment in daily clinical practice. Combining surgery with antiinflammatory treatment warrants further investigation.
引用
收藏
页码：69 / +
页数：13
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