Fetal Surgery for Myelomeningocele

被引:12
|
作者
Hirose, Shinjiro [1 ]
Farmer, Diana L. [1 ]
机构
[1] Univ Calif San Francisco, Dept Surg, Div Pediat Surg, Fetal Treatment Ctr, San Francisco, CA 94143 USA
关键词
Fetal surgery; Myelomeningocele; Hydrocephalus; Shunt; SHUNT-DEPENDENT HYDROCEPHALUS; IN-UTERO REPAIR; ALLOWS NORMAL DEVELOPMENT; SPINAL-CORD INJURY; HINDBRAIN HERNIATION; MODEL; SHEEP; BIFIDA; SKIN; PREMATURITY;
D O I
10.1016/j.clp.2009.03.008
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Fetal intervention for myelomeningocele (MMC) may improve hydrocephalus and hindbrain herniation associated with the Arnold-Chiari II malformation and may reduce the need for ventriculoperitoneal shunting. As of now, there is little evidence that prenatal repair of MMC: improves neurologic function. MMC is the first nonlethal disease under consideration and study for fetal surgery. As a result, potential improvements in outcome must be balanced with maternal safety and well-being, in addition to that of the unborn patient.
引用
收藏
页码:431 / +
页数:9
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