Delayed lethal response to Aspergillus fumigatus infection in sarcoma 180 tumor-bearing mice

被引：0
|
作者：
Okawa, Y
Murata, Y
Suzuki, M
Ito, M
Hotchi, M
Suzuki, S
机构：
[1] Tohoku Pharmaceut Univ, Dept Hyg Chem 2, Aoba Ku, Sendai, Miyagi 9818558, Japan
[2] Tohoku Pharmaceut Univ, Dept Microbiol, Aoba Ku, Sendai, Miyagi 9818558, Japan
[3] Shinshu Univ, Sch Med, Dept Pathol, Matsumoto, Nagano 390, Japan
来源：
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY | 2002年 / 34卷 / 02期
关键词：
tumor-bearing mouse; infection; fungal element in tissue; transferrin; Aspergillus fumigatus;
D O I：
10.1016/S0928-8244(02)00347-4
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A longer survival and a decrease in the number of fungal cells in kidneys and brain were observed in groups of mice inoculated with Aspergillus fumigatus conidia 2-3 weeks (especially 3 weeks) after sarcoma 180 tumor transplantation compared to groups of non-tumor-bearing (control) mice inoculated with fungal cells only. The 3-4-week tumor-bearing mice had significantly decreased levels of serum iron and increased levels of unbound iron binding capacity in the serum compared to those of the non-tumor-bearing mice. (C) 2002 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码：113 / 117
页数：5
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