Biomonitoring of polycyclic aromatic hydrocarbons in human urine

被引：0

作者：

Jacob, R ^{[1
]}

Seidel, A ^{[1
]}

机构：

[1] Prof Dr Gernot Grimmer Stiftung, Biochem Inst Umweltcarcinogene, D-22927 Grosshansdorf, Germany

来源：

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 2002年 / 778卷 / 1-2期

关键词：

polynuclear aromatic hydrocarbons;

D O I：

暂无

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Measurement of polycyclic aromatic hydrocarbons (PAH) metabolites in human urine is the method of choice to determine occupational and/or environmental exposure of an individual to PAH, in particular, when multiple routes of exposure have to be taken into account. Requirements for methods of biomonitoring PAH metabolites in urine are presented. Studies using 1-hydroxypyrene or phenanthrene metabolites including its phenols and dihydrodiols are summarized. The role of these PAH metabolites as established biomarkers and also more recent developments of PAH biomonitoring are discussed; (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：31 / 47

页数：17

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