Drug-Binding to Distinct Sites of the Multidrug Exporter P-Glycoprotein

被引:0
|
作者
Urbatsch, Ina [1 ]
Bui, Anthony A. [1 ]
Zapata, Joel [1 ]
Swartz, Douglas J. [2 ]
Katz, Courtney [1 ]
Singh, Anukriti [1 ]
Weber, Joachim [1 ]
机构
[1] Texas Tech Univ, Hlth Sci Ctr, Dept Cell Biol & Biochem, Lubbock, TX 79430 USA
[2] Lubbock Christian Univ, Lubbock, TX USA
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
338-Pos
引用
收藏
页码:69A / 70A
页数:2
相关论文
共 50 条
  • [1] Drug-binding to distinct sites of the multidrug exporter P-glycoprotein
    Tran, Nghi
    Urbatsch, Ina
    Swartz, Douglas J.
    Singh, Anukriti
    Katz, Courtney
    Jackson, Benjamin T.
    Weber, Joachim
    BIOPHYSICAL JOURNAL, 2022, 121 (03) : 342A - 342A
  • [2] Drug-binding to Distinct Sites of the Multidrug Exporter P-glycoprotein
    Urbatsch, Ina L.
    Swartz, Douglas J.
    Singh, Anukriti
    Katz, Courtney
    Jackson, Benjamin T.
    Weber, Joachim
    BIOPHYSICAL JOURNAL, 2020, 118 (03) : 19A - 19A
  • [3] Drug-Binding to Distinct Site of the Multidrug Exporter P-Glycoprotein Monitored by Tryptophan Fluorescence
    Urbatsch, Ina
    Swartz, Douglas J.
    Singh, Anukriti
    Katz, Courtney
    Gautam, Sakshi
    Weber, Joachim
    BIOPHYSICAL JOURNAL, 2019, 116 (03) : 126A - 126A
  • [4] EFFECTS OF NONIONIC DETERGENTS ON P-GLYCOPROTEIN DRUG-BINDING AND REVERSAL OF MULTIDRUG-RESISTANCE
    ZORDANNUDO, T
    LING, V
    LIU, Z
    GEORGES, E
    CANCER RESEARCH, 1993, 53 (24) : 5994 - 6000
  • [5] The drug-binding pocket of the human multidrug resistance P-glycoprotein is accessible to the aqueous medium
    Loo, TW
    Bartlett, MC
    Clarke, DM
    BIOCHEMISTRY, 2004, 43 (38) : 12081 - 12089
  • [6] Vanadate trapping of nucleotide at the ATP-binding sites of human multidrug resistance P-glycoprotein exposes different residues to the drug-binding site
    Loo, TW
    Clarke, DM
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (06) : 3511 - 3516
  • [7] Probing Drug-Binding Pathways in P-Glycoprotein with Ensemble Docking
    Thangapandian, Sundarapandian
    Tajkhorshid, Emad
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 791A - 791A
  • [8] Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein
    Mittra, Rituparna
    Pavy, Megan
    Subramanian, Nanditha
    George, Anthony M.
    O'Mara, Megan L.
    Kerr, Ian D.
    Callaghan, Richard
    BIOCHEMICAL PHARMACOLOGY, 2017, 123 : 19 - 28
  • [9] MODULATION OF ATP AND DRUG-BINDING BY MONOCLONAL-ANTIBODIES AGAINST P-GLYCOPROTEIN
    GEORGES, E
    ZHANG, JT
    LING, V
    JOURNAL OF CELLULAR PHYSIOLOGY, 1991, 148 (03) : 479 - 484
  • [10] Transmembrane segment 1 of human P-glycoprotein contributes to the drug-binding pocket
    Loo, Tip W.
    Bartlettt, M. Claire
    Clarke, David M.
    BIOCHEMICAL JOURNAL, 2006, 396 : 537 - 545