Progress in the use of microemulsions for transdermal and dermal drug delivery

被引：26
|
作者：
Ita, Kevin [1 ,2 ]
机构：
[1] Touro Univ, Coll Pharm, Mare Island-Vallejo, CA USA
[2] Touro Univ, Coll Pharm, Mare Isl Vallejo, CA 94592 USA
来源：
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY | 2017年 / 22卷 / 04期
关键词：
Drug delivery; microemulsion; oil phase; skin; surfactant; transdermal; IN-VIVO; SKIN PENETRATION; VITRO; MICRONEEDLES; FORMULATION; MODEL; ACID; BIOAVAILABILITY; OPTIMIZATION; PERMEATION;
D O I：
10.3109/10837450.2016.1148722
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Transdermal drug delivery continues to attract considerable interest in the scientific community. However, due to the hindrance provided by the stratum corneum, it is not possible to deliver most medications in therapeutically significant amounts. One of the ways of increasing the penetration of drugs across the skin is through the use of microemulsions (MEs). This review focuses on the role of MEs in enhancing topical and transdermal drug delivery.
引用
收藏
页码：467 / 475
页数：9
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